Breast Cancer
New breast cancer research from Norwegian University Science & Technology described
Published in Women's Health Weekly, April 8th, 2010
"The purpose of this study was to evaluate the use of dynamic contrast-enhanced (DCE) MRI, in vivo H-1 MRS and ex vivo high resolution magic angle spinning (HR MAS) MRS of tissue samples as methods to detect early treatment effects of docetaxel in a breast cancer xenograft model (MCF-7) in mice. MCF-7 cells were implanted subcutaneously in athymic mice and treated with docetaxel (20, 30, and 40 mg/kg) or saline six weeks later," investigators in Trondheim, Norway report.
"DCE-MRI and in vivo H-1 MRS were performed on a 7T MR system three days after treatment. The dynamic images were used as input for a two-compartment model, yielding the vascular parameters K-trans and...
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