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Ovarian Cancer Prognosis

Research from Dana-Farber Cancer Institute, Department of Medical Oncology broadens understanding of ovarian cancer prognosis

Published in Women's Health Weekly, April 15th, 2010

Data detailed in 'p53 autoantibodies as potential detection and prognostic biomarkers in serous ovarian cancer' have been presented. "This study examined the value of serum p53 autoantibodies (p53-AAb) as detection and prognostic biomarkers in ovarian cancer. p53-AAb were detected by ELISA in sera obtained preoperatively from women undergoing surgery for a pelvic mass," scientists in the United States report.

"This group included women subsequently diagnosed with invasive serous ovarian cancer (n=60), nonserous ovarian cancers (n=30), and women with benign disease (n=30). Age-matched controls were selected from the general population (n=120). Receiver operating...

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