Current study results from the report, 'A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory,' have been published. "Lynch syndrome (LS) is caused by mutations in mismatch repair genes and is characterized by a high cumulative risk for the development of mainly colorectalcarcinoma and endometrial carcinoma. Early detection of LS is important since surveillance can reduce morbidity and mortality," researchers in Netherlands report.
"However, the diagnosis of LS is complicated by the absence of a pre-morbid phenotype and germline mutation analysis is expensive and time consuming. Therefore it is standard practice to precede...
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