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Breast Cancer

Research conducted at University Medical Center has provided new information about breast cancer

Published in Women's Health Weekly, June 10th, 2010

"We performed a feasibility study to determine the optimal dosage and time of administration of the monoclonal antibody zirconium-89 (Zr-89)-trastuzumab to enable positron emission tomography (PET) imaging of human epidermal growth factor receptor 2 (HER2)-positive lesions. Fourteen patients with HER2-positive metastatic breast cancer received 37 MBq of Zr-89-trastuzumab at one of three doses (10 or 50 mg for those who were trastuzumab-naive and 10 mg for those who were already on trastuzumab treatment)," scientists writing in the journal Clinical Pharmacology & Therapeutics report.

"The patients underwent at least two PET scans between days 2 and 5. The results...

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