Breast Cancer
New breast cancer study findings have been reported from University of Massachusetts, Department of Cancer Biology
Published in Women's Health Weekly, July 22nd, 2010
Scientists discuss in 'miR-10b targets Tiam1: implications for Rac activation and carcinoma migration' new findings in breast cancer. "Understanding the mechanisms by which specific microRNAs regulate cell migration and invasion is a timely and significant problem in cancer cell biology. miR-10b is of interest in this regard because its expression is altered in breast and other cancers. Our analysis of potential miR-10b targets identified Tiam1 (T lymphoma invasion and metastasis 1), a guanidine exchange factor for Rac," researchers in the United States report.
"We demonstrate, using an miR-10b synthetic precursor, expression vector, and antisense oligonucleotide, that...
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