Breast Cancer
Studies from J. del Valle and colleagues provide new data on breast cancer
Published in Women's Health Weekly, August 5th, 2010
Fresh data on breast cancer are presented in the report 'Identification and comprehensive characterization of large genomic rearrangements in the BRCA1 and BRCA2 genes.' "Large genomic rearrangements are estimated to account for approximately 5-10% of all disease-causing mutations in BRCA1 and BRCA2 genes in patients with hereditary breast and ovarian cancer syndrome (HBOC). We use MRC-Holland Multiplex Ligation-dependent Probe Amplification (MLPA) to screen for such rearrangements in patients with HBOC and as a first step in our genetic testing workflow," scientists in Barcelona, Spain report.
"The technique was applied to a set of 310 independent patients and detected...
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