Breast Cancer
Study results from University of Bonn, Institute of Pharmacy provide new insights into breast cancer
Published in Women's Health Weekly, September 30th, 2010
New investigation results, 'Specific inhibitors of the breast cancer resistance protein (BCRP),' are detailed in a study published in Chemmedchem. "A new class of specific breast cancer resistance protein (BCRP) inhibitors was identified, showing no inhibition of the ATP binding cassette (ABC) transporters P-gp and MRP1. Some of these modulators inhibit BCRP with high potency; they are only slightly less potent than Ko143 and could serve as promising lead structures for the design of novel effective BCRP inhibitors," scientists in Bonn, Germany report.
"These inhibitors are structurally related to tariquidar (XR9576) and belong to a library of...
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