Breast Cancer
Research reports on breast cancer from Case Western Reserve University, Department of Pharmacology provide new insights
Published in Women's Health Weekly, October 7th, 2010
A new study, 'HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42,' is now available. According to recent research published in the Journal of Biological Chemistry, "Breast cancers that overexpress the receptor tyrosine kinase ErbB2/HER2/Neu result in poor patient outcome because of extensive metastatic progression. Herein, we delineate a molecular mechanism that may govern this malignant phenotype."
"ErbB2 induction of migration requires activation of the small GTPases Rac1 and Cdc42. The ability of ErbB2 to activate these small GTPases necessitated expression of p120 catenin, which is itself...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
More Articles from Women's Health Weekly
- Breast Cancer
Breastcancer.org Launches Its First-Ever Mobile App - Breast Cancer
Celldex Therapeutics Announces Initiation of Randomized Phase 2b Clinical Trial of CDX-011 in Advanced Breast Cancer - Breast Cancer
Celsion Announces ThermoDox(R) Abstract Accepted at the 2010 Breast Cancer Symposium - Breast Cancer
Data from University Hospital, Institute for Cancer Research advance knowledge in breast cancer - Escherichia
Data on Escherichia published by researchers at University Medical Center, Department of Biochemistry - Breast Cancer
Data on breast cancer discussed by researchers at University of Louisville, Department of Surgery - More from this issue of Women's Health Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
