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Breast Cancer

New breast cancer study results reported from Kyushu University, Medical Institute of Bioregulation

Published in Women's Health Weekly, October 14th, 2010

Data detailed in 'Correlated expression of CD47 and SIRPA in bone marrow and in peripheral blood predicts recurrence in breast cancer patients' have been presented. "CD47 plays a variety of roles in intercellular signaling. Herein, we focused on the clinicopathologic significance of CD47 expression in human breast cancer," scientists in Oita, Japan report.

"Our data suggest that the correlation between CD47 and signal regulatory protein a (SIRPA) expression may play a key role in the progression of breast cancer. Quantitative real-time PCR was used to evaluate CD47 mRNA and SIRPA mRNA expression in bone marrow and in peripheral blood from 738 cases of breast cancer. In...

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