Breast Cancer
Data on breast cancer described by researchers at University of British Columbia, Life Sciences Institute
Published in Women's Health Weekly, October 14th, 2010
Investigators publish new data in the report 'Matricellular protein CCN3 (NOV) regulates actin cytoskeleton reorganization.' "CCN3 (NOV), a putative ligand for integrin receptors, is tightly associated with the extracellular matrix and mediates diverse cellular functions, including cell adhesion and proliferation. CCN3 has been shown to negatively regulate growth although it promotes migration in a cell type-specific manner," scientists in Vancouver, Canada report.
"In this study, overexpression of CCN3 reduces growth and increases intercellular adhesion of breast cancer cells. Interestingly, CCN3 overexpression also led to the formation of multiple pseudopodia that are...
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