Fresh data on ovarian cancer are presented in the report 'Role of cell surface molecules and autologous ascitic fluid in determining efficiency of adenoviral transduction of ovariancancer cells.' "Adenovirus is the most frequently used virus in gene therapy clinical trials. There have been conflicting reports on the ability of adenovirus to transduce primary ovarian cancer samples and the expression of relevant cell surface molecules," scientists in Leeds, the United Kingdom report.
"These factors were examined using primary ovarian cancer cells cultured from ascites and solid tumor to gain insights into the clinical use of adenovirus in ovarian cancer. The level of...
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