Breast Cancer

New breast cancer study findings have been reported by scientists at National Cancer Center

Published in Women's Health Weekly, October 14th, 2010

Scientists discuss in 'Genetic alterations of FGF receptors: an emerging field in clinical cancer diagnostics and therapeutics' new findings in breast cancer. According to a study from Tokyo, Japan, "Evaluation of: Turner N, Pearson A, Sharpe R et al. FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. Cancer Res. 70(5), 2085-2094 (2010)."

"FGF receptor (FGFR) family members are aberrantly activated during carcinogenesis due to gene amplification, chromosomal translocation and missense mutation. FGFR1 is preferentially amplified in estrogen receptor-positive breast cancer, whereas FGFR2 is amplified in triple-negative...

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Source: Women's Health Weekly (2010-10-14)

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