Ovarian Cancer
Reports from University of Sydney, Kolling Institute of Medical Research add new data to research in ovarian cancer
Published in Women's Health Weekly, November 4th, 2010
A report, 'The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor,' is newly published data in Endocrine-related Cancer. According to a study from Sydney, Australia, "The chemokine CXCL1 is elevated in plasma and ascites from patients with ovarian cancer. We have previously shown that CXCL1 is a marker of phosphatidylinositol 3-kinase signalling in epithelial ovarian cancer (EOC) cell lines, a pathway that is commonly activated in ovarian tumours."
"To investigate whether CXCL1 also has functional significance in ovarian cancer, this chemokine was either down-regulated using siRNAs...
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