Menopause
Recent findings in menopause described by researchers from University of Michigan, Comprehensive Cancer Center
Published in Women's Health Weekly, November 11th, 2010
Fresh data on menopause are presented in the report 'Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results.' "We previously reported that the ESR1 XbaI genotypes were associated with baseline and tamoxifen-induced serum lipid profiles. The analysis in that study was carried out by PCR followed by restriction-enzyme digestion," researchers in the United States report.
"After reanalysis using more robust TaqMan assays, the findings related to ~10% of the genotypes for the ESR1 XbaI single-nucleotide polymorphism (SNP) were revised. For the other genotypes (i.e., ESR1 PvuII, ESR2, and CYP2D6), the results...
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