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Cervical Cancer

Data from A. Martinez et al provide new insights into cervical cancer

Published in Women's Health Weekly, November 18th, 2010

"Aims of the study were to identify the incidence of micrometastases in negative para-aortic lymph nodes, and to assess the utility of ultrastaging in histologic evaluation of para-aortic lymph nodes. Patients with advanced cervical cancer and negative para-aortic lymph nodes after routine histology examination were included," investigators in Toulouse, France report.

"Paraffin-embedded tissue blocks were cut into 5-mu m-thick slides at step serial sections at 200-mu m intervals until there was no lymph node tissue left. 7 to 14 slides were obtained per lymph node and an immunohistochemistry staining with anti-cytokeratin antibody (EA1/EA3) was performed. 581...

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