Genetics and Breast Cancer
New genetics and breast cancer study findings reported from London Research Institute
Published in Women's Health Weekly, November 18th, 2010
Research findings, 'Targeting chromosomal instability and tumour heterogeneity in HER2-positive breast cancer,' are discussed in a new report. According to recent research from London, the United Kingdom, "Chromosomal instability (CIN) is a common cause of tumor heterogeneity and poor prognosis in solid tumours and describes cell-cell variation in chromosome structure or number across a tumor population. In this article we consider evidence suggesting that CIN may be targeted and may influence response to distinct chemotherapy regimens, using HER2-positive breast cancer as an example."
"Pre-clinical models have indicated a role for HER2 signalling in initiating CIN and...
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