Breast Cancer

Research on breast cancer detailed by scientists at Albert Einstein College of Medicine, College of Medicine

Published in Women's Health Weekly, December 23rd, 2010

2010 DEC 23 -- "The considerable uncertainty regarding cancer risks associated with inherited mutations of BRCA2 is due to unknown factors. To investigate whether common genetic variants modify penetrance for BRCA2 mutation carriers, we undertook a two-staged genome-wide association study in BRCA2 mutation carriers," scientists in the United States report.

"In stage 1 using the Affymetrix 6.0 platform, 592,163 filtered SNPs genotyped were available on 899 young (, 40 years) affected and 804 unaffected carriers of European ancestry. Associations were evaluated using a survival-based score test adjusted for familial correlations and stratified by country of...

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Source: Women's Health Weekly (2010-12-23)

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