Breast Cancer

Reports on breast cancer findings from University of Alabama provide new insights

Published in Women's Health Weekly, December 23rd, 2010

2010 DEC 23 -- "The status of estrogen receptor-alpha (ER alpha) is critical to the clinical prognosis and therapeutic approach in breast cancer. ER alpha-negative breast cancer is clinically aggressive and has a poor prognosis because of the lack of hormone target-directed therapies," researchers in the United States report.

"Previous studies have shown that epigenetic regulation plays a major role in ER alpha silencing in human breast cancer cells. Dietary green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), is believed to be an anticancer agent in part through its regulation of epigenetic processes. In our current studies, we found that EGCG can...

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Source: Women's Health Weekly (2010-12-23)

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