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Breast Cancer

Catalan Institute of Oncology details research in breast cancer

Published in Women's Health Weekly, December 30th, 2010

2010 DEC 30 -- New research, 'Exploring the link between germline and somatic genetic alterations in breast carcinogenesis,' is the subject of a report. "Recent genome-wide association studies (GWASs) have identified candidate genes contributing to cancer risk through low-penetrance mutations. Many of these genes were unexpected and, intriguingly, included well-known players in carcinogenesis at the somatic level," researchers in Barcelona, Spain report.

"To assess the hypothesis of a germline-somatic link in carcinogenesis, we evaluated the distribution of somatic gene labels within the ordered results of a breast cancer risk GWAS. This analysis suggested...

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