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Bone Research

Studies from Federico II University provide new data on bone research

Published in Women's Health Weekly, January 6th, 2011

2011 JAN 6 -- New investigation results, 'Role of IGF-I on PTH effects on bone,' are detailed in a study published in Journal of Endocrinological Investigation. According to recent research from Naples, Italy, "IGF-I and PTH have synergistic actions on bone and some effects of the anabolic actions of PTH are mediated by local production of IGF-I, as has been shown in vitro and in vivo studies both in animals and humans. PTH can induce skeletal IGF-I expression both in vitro and in vivo."

"In chondrocytes, IGF-I synthesis is under GH control, whereas in osteoblasts its synthesis is fundamentally under the control of PTH. PTH stimulates the synthesis...

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