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Cysteine Endopeptidases

Study results from Aristotle University update understanding of cysteine endopeptidases

Published in Women's Health Weekly, January 13th, 2011

2011 JAN 13 -- "When apoptosis is disrupted, the transformed cells can survive, proliferate, and evolve into a malignancy. The strictly conserved caspase genes and the reliable experimental data clearly show that some caspases play a crucial role in apoptosis even if some of them have no apoptotic activity and others exhibit both apoptotic and nonapoptotic properties," scientists in Thessaloniki, Greece report.

"Although caspase-2 belongs to initiator caspases, its normal role remains unclear. Experimental studies have shown that it is primarily necessary for the execution of apoptosis in mutagenic cells. Human caspase-5 is classified as an inflammatory...

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