Spontaneous Abortion
Studies from Ludwik Hirszfeld Institute of Immunology and Experimental Therapy Further Understanding of Spontaneous Abortion
Published in Women's Health Weekly, January 20th, 2011
2011 JAN 20 -- New investigation results, 'HLA-C C1C2 heterozygosity may protect women bearing the killer immunoglobulin-like receptor AA genotype from spontaneous abortion,' are detailed in a study published in Journal of Reproductive Immunology. "Spontaneous abortion is the most common complication of human pregnancy. Natural killer (NK) cells expressing killer immunoglobulin-like receptors (KIRs), which may recognize HLA-C (i.e. its C1 or C2 groups) on trophoblast cells, constitute a large leukocyte population in the endometrium," scientists in Wroclaw, Poland report.
"This study investigated whether genetic polymorphisms in the KIR and HLA-C...
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