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Breast Cancer

Data on Breast Cancer Reported by M. Faouzi and Co-Researchers

Published in Women's Health Weekly, January 20th, 2011

2011 JAN 20 -- New research, 'Down-regulation of Orai3 arrests cell-cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells,' is the subject of a report. "Breast cancer (BC) is the leading cancer in the world in terms of incidence and mortality in women. However, the mechanism by which BC develops remains largely unknown," investigators in Amiens, France report.

"The increase in cytosolic free Ca(2+) can result in different physiological changes including cell growth and death. Orai isoforms are highly Ca(2+) selective channels. In the present study, we analyzed Orai3 expression in normal and cancerous breast...

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