Ovarian Cancer

New Findings Reported from University of Manchester Describe Advances in Ovarian Cancer

Published in Women's Health Weekly, January 27th, 2011

2011 JAN 27 -- "Recent candidate gene and genome wide association studies have revealed novel loci associated with an increased risk of breast cancer. We evaluated the effect of these breast cancer associated variants on ovarian cancer risk in individuals with familial ovarian cancer both with and without BRCA1 or BRCA2 mutations," scientists in Manchester, the United Kingdom report.

"A total of 158 unrelated white British women (54 BRCA1/2 mutation positive and 104 BRCA1/2 mutation negative) with familial ovarian cancer were genotyped for FGFR2, TNRC9/TOX3 and CASP8 variants. The p.Asp302His CASP8 variant was associated with reduced ovarian cancer risk in...

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Source: Women's Health Weekly (2011-01-27)

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