Ovarian Cancer

New Findings Reported from B. Wang and Co-Authors Describe Advances in Ovarian Cancer

Published in Women's Health Weekly, February 10th, 2011

2011 FEB 10 -- In this recent report, researchers in the United States conducted a study "To assess the role of active immunotherapy targeting VEGF with a peptide vaccine as a potential treatment for ovarian cancer. A peptide vaccine targeting antigenic B-cell epitopes of VEGF were identified and linked to a promiscuous T-cell epitope."

"Elicited antibodies were assessed for their ability to recognize the VEGF protein, inhibit angiogenesis, inhibit the interaction of VEGF with its receptor, and inhibit cancer growth in mice. Following immunization, high-titered elicited antibodies were shown to be specific for the full-length VEGF protein by ELISA and...

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Source: Women's Health Weekly (2011-02-10)

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