Breast Cancer

Research Conducted at University of Tehran Has Updated Our Knowledge about Breast Cancer

Published in Women's Health Weekly, February 17th, 2011

2011 FEB 17 -- "A series of dibenzyl-gamma-butyrolactones bearing a hydroxyl group at the benzylic position of 3-benzyl group were synthesized as hydrated analogue of isochaihulactone and evaluated against breast cancer human cell lines (MDA-M231, MCF-7 and T47D)," researchers in Iran report.

"The target compounds were synthesized in 7 steps from known lactone; (S)-(+)-gamma-benzyloxymethyl-gamma-butyrolactone," wrote B.H. Alizadeh and colleagues, University of Tehran.

The researchers concluded: "The key step was the aldol condensation between (+)-®-beta-(benzo[d][1,3]dioxol-5-ylmethyl)-gamma-butyrolactone and substituted...

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Source: Women's Health Weekly (2011-02-17)

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