Breast Cancer
Research Reports on Breast Cancer from Fox Chase Cancer Center Provide New Insights
Published in Women's Health Weekly, February 17th, 2011
2011 FEB 17 -- Research findings, 'Expression of estrogen receptor alpha with a Tet-off adenoviral system induces G0/G1 cell cycle arrest in SKBr3 breast cancer cells,' are discussed in a new report. According to recent research from the United States, "Endocrine therapies targeting estrogen action are pivotal for the prevention and treatment of ER-positive breast cancers. Previous studies sought to recreate hormone responsiveness by the stable expression of ERalpha in the ER-negative MDA-MB-231 breast cancer cells."
"Paradoxically, estrogen inhibits breast cancer cell growth when an exogenous ERalpha is expressed. In this study, we have built on previous...
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