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Breast Cancer

Data from Baylor College of Medicine, Cancer Center Provide New Insights into Breast Cancer

Published in Women's Health Weekly, February 17th, 2011

2011 FEB 17 -- New research, 'Mechanisms of endocrine resistance in breast cancer,' is the subject of a report. "The estrogen receptor (ER) pathway plays a pivotal role in breast cancer development and progression. Endocrine therapy to block the ER pathway is highly effective, but its usefulness is limited by common intrinsic and acquired resistance," researchers in the United States report.

"Multiple mechanisms responsible for endocrine resistance have been proposed and include deregulation of various components of the ER pathway itself, alterations in cell cycle and cell survival signaling molecules, and the activation of escape pathways that can provide...

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