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Ovarian Hyperstimulation Syndrome

Research from University of Valencia Yields New Findings on Ovarian Hyperstimulation Syndrome

Published in Women's Health Weekly, March 17th, 2011

2011 MAR 17 -- Data detailed in 'Physiology and pathology of ovarian hyperstimulation syndrome' have been presented. "Ovarian hyperstimulation syndrome (OHSS) occurs when ovaries primed with follicle-stimulating hormone/leuteinizing hormone (LH) are subsequently exposed to human chorionic gonadotropin (hCG). The ultimate pathophysiological step underlying this clinical picture is increased vascular permeability (VP)," scientists in Valencia, Spain report.

"With the administration of hCG, the expression vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR-2) mRNA increases significantly rising to a maximum coinciding with peaked VP....

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