Breast Cancer

Data from University of Texas Southwestern Medical Center Provide New Insights into Breast Cancer

Published in Women's Health Weekly, March 24th, 2011

2011 MAR 24 -- "Triple-negative (TN) breast carcinoma is associated with a higher recurrence rate and shorter survival and lacks the benefit of specific therapy. TN tumors usually express high levels of Ki-67 and p53 that are considered prognostic markers for breast cancer," investigators in the United States report.

"We compared Ki-67 and p53 expression between TN and high-grade non-TN invasive carcinomas in a total of 214 cases and investigated an association between their expression and axillary nodal metastasis in these tumors. Our findings demonstrate that TN tumors are associated with significantly higher expression of Ki-67 and p53 compared with...

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Source: Women's Health Weekly (2011-03-24)

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