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Breast Cancer

ACE inhibitors may increase risk of recurrence in breast cancer survivors

Published in Women's Health Weekly, May 5th, 2011

2011 MAY 5 -- ACE inhibitors, commonly used to control high blood pressure and heart failure in women, may be associated with an increased risk of recurrence in women who have had breast cancer, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

Beta blockers, used to control high blood pressure and cardiac arrhythmias, appear to have a protective effect, helping to prevent recurrence. When used together, beta blockers appear to help ameliorate the negative affect of ACE inhibitors, said Dr. Patricia Ganz, director of cancer prevention and control research at UCLA's Jonsson Cancer Center and first author of the study.

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