Osteoporosis

Amgen and UCB Announce Positive Phase 2 Results of AMG 785/CDP7851 in Patients With Postmenopausal Osteoporosis PMO

Published in Women's Health Weekly, May 5th, 2011

2011 MAY 5 -- Amgen (NASDAQ: AMGN) and UCB (Euronext Brussels: UCB) announced positive top-line results from their Phase 2 clinical study comparing sclerostin-antibody AMG 785/CDP7851 to placebo in postmenopausal women with low bone mineral density (BMD) for the treatment of postmenopausal osteoporosis (PMO).

This Phase 2 study met its primary endpoint, demonstrating significant increases in lumbar spine bone mineral density at month 12 for the AMG 785/CDP7851 active arms versus the placebo arm. In addition, AMG 785/CDP7851 compared positively with the two active comparators, teriparatide and alendronate.

The overall incidence of adverse...

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Source: Women's Health Weekly (2011-05-05)

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