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Ovarian Cancer

Researchers at Institute of Oncology Have Published New Data on Ovarian Cancer

Published in Women's Health Weekly, May 12th, 2011

2011 MAY 12 -- Data detailed in 'The CYP17A1 -34T > C polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers' have been presented. "Exposure to estrogen has a major effect on breast cancer risk. A polymorphism (-34 T > C; rs743572) in the cytochrome P450c17alpha gene (CYP17A1) encoding an enzyme which controls estrogen levels was reportedly associated with breast cancer risk in average risk populations," scientists in Tel Hashomer, Israel report.

"The effect of this polymorphism on breast or ovarian cancer risk for BRCA1 and BRCA2 mutation carriers has not been thoroughly investigated. With this aim, 2,221 BRCA1 and BRCA2 mutation...

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