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Breast Cancer

Data on Breast Cancer Published by Researchers at Georgetown University School of Medicine

Published in Women's Health Weekly, May 19th, 2011

2011 MAY 19 -- Researchers detail in 'Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer,' new data in Breast Cancer. According to recent research published in the journal Breast Cancer Research and Treatment, "The interferon regulatory factor-1 (IRF1) gene, localized on chromosome 5q31.1, is mutated or rearranged in several cancers including some hematopoietic and gastric cancers. However, whether loss of IRF1 occurs in sporadic breast cancer is unknown."

"Loss of 5q12-31 is reported in 11% of sporadic breast cancers, and high-resolution array-CGH studies have shown loss at 5q31.1 in 50% of breast...

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