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Breast Cancer

Brigham Young University Details Research in Breast Cancer

Published in Women's Health Weekly, May 26th, 2011

2011 MAY 26 -- "Estrogen receptors (ERs) are normally expressed in breast tissues and mediate hormonal functions during development and in female reproductive physiology. In the majority of breast cancers, ERs are involved in regulating tumor cell proliferation and serve as prognostic markers and therapeutic targets in the management of hormone-dependent tumors," scientists in Provo, United States report.

"At the molecular level, ERs function as ligand-dependent transcription factors and activate target-gene expression following hormone stimulation. Recent transcriptomic and whole-genome-binding studies suggest, however, that ligand-activated ERs can also...

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