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Hypertension

New Hypertension Research from National Institute on Aging Described

Published in Women's Health Weekly, June 9th, 2011

2011 JUN 9 -- According to a study from Baltimore, United States, "Marinobufagenin (MBG), a bufadienolide cardiotonic steroid, induces cardiovascular fibrosis. Because levels of MBG in preeclampsia are increased, and anti-MBG monoclonal antibody reduces blood pressure (BP) in a rat model of preeclampsia, we hypothesized that in preeclampsia, elevated MBG levels would be associated with the development of fibrosis in feto-placental circulation and with impairment of vascular relaxation."

"We studied 16 patients with preeclampsia (systolic BP=150 +/- 4 mmHg; 28 +/- 2 years, 37 +/- 1 weeks gestational age) and 14 gestational age-matched normal pregnant women...

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