Ovarian Cancer
Research from University of Alberta Reveals New Findings on Ovarian Cancer
Published in Women's Health Weekly, June 23rd, 2011
2011 JUN 23 -- A new study, "Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays," is now available. According to recent research from Edmonton, Canada, "Genetic screening of the breast and ovarian cancer susceptibility gene BRCA1 has uncovered a large number of variants of uncertain clinical significance. Here, we use biochemical and cell-based transcriptional assays to assess the structural and functional defects associated with a large set of 117 distinct BRCA1 missense variants within the essential BRCT domain of the BRCA1 protein that have been documented in individuals with a family history of breast or ovarian...
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