Clinical Investigation

Reports from University of Pennsylvania Medical Center Advance Knowledge in Clinical Investigation

Published in Women's Health Weekly, June 30th, 2011

2011 JUN 30 -- "Pelvic organ prolapse (POP) is a disabling disorder in women characterized by a loss of pelvic floor support leading to the herniation of the uterus into or through the vagina," scientists in Philadelphia, United States report.

"POP is a complex problem that likely involves multiple mechanisms, and available therapies are limited," wrote G.M. Northington and colleagues, University of Pennsylvania Medical Center.

The researchers concluded: "In this issue of the JCI, Budatha et al. explore the dual role carried out by fibulin-5 in facilitating the assembly of normal elastic fibers and inhibiting MMP-9 activity, revealing a...

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Source: Women's Health Weekly (2011-06-30)

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