Small Interference RNAs (siRNAs)

Data on Small Interference RNAs (siRNAs) Discussed by Researchers at Loyola University

Published in Women's Health Weekly, November 10th, 2011

2011 NOV 10 -- "Women with triple-negative breast cancer have the worst prognosis, frequently present with metastatic tumors and have few targeted therapy options. Notch-1 and Notch-4 are potent breast oncogenes that are overexpressed in triple-negative and other subtypes of breast cancer," scientists in Maywood, Illinois report.

"PEA3, an ETS transcription factor, is also overexpressed in triple-negative and other breast cancer subtypes. We investigated whether PEA3 could be the critical transcriptional activator of Notch receptors in MDA-MB-231 and other breast cancer cells. Real-time PCR and Western blot analysis were performed to detect Notch-1,...

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Source: Women's Health Weekly (2011-11-10)

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