Breast Cancer

New Data from University of Wurzburg Illuminate Research in Breast Cancer

Published in Women's Health Weekly, December 1st, 2011

2011 DEC 1 -- "BRCA1 is a major gatekeeper of genomic stability. Acting in multiple central processes like double-strand break repair, centrosome replication, and checkpoint control, BRCA1 participates in maintaining genomic integrity and protects the cell against genomic instability," investigators in Wurzburg, Germany report.

"Chromosomal instability (CIN) as part of genomic instability is an inherent characteristic of most solid tumors and is also involved in breast cancer development. In this study, we determined the extent of CIN in 32 breast cancer tumors of women with a BRCA1 germline mutation compared to 62 unselected breast cancers. We applied...

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Source: Women's Health Weekly (2011-12-01)

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