Ovarian Cancer
Scientists at Southeast University Target Ovarian Cancer
Published in Women's Health Weekly, January 5th, 2012
2012 JAN 5 -- Data detailed in "Effect of downregulated ß-catenin on cell proliferative activity, the sensitivity to chemotherapy drug and tumorigenicity of ovarian cancer cells" have been presented. "The role of Wnt/ß-catenin signaling pathway in the etiology and/or progression of ovarian cancer has been well documented. It was demonstrated that ovarian cancer constantly exhibit constitutive activation of canonical Wnt signaling, usually as a result of oncogenic mutations that stabilize and dysregulate the ß-catenin protein," scientists in Nanjing, People's Republic of China report.
"In this study, we transfected an expression vector-based...
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