Pregnancy
Investigators at University of Oxford Zero in on Pregnancy
Published in Women's Health Weekly, January 5th, 2012
2012 JAN 5 -- Investigators discuss in "ST2 and IL-33 in pregnancy and pre-eclampsia" new findings in Pregnancy. "Normal pregnancy is associated with a mild systemic inflammatory response and an immune bias towards type 2 cytokine production, whereas pre-eclampsia is characterized by a more intense inflammatory response, associated with endothelial dysfunction and a type 1 cytokine dominance. Interleukin (IL)-33 is a newly described member of the IL-1 family, which binds its receptor ST2L to induce type 2 cytokines," scientists in Oxford, United Kingdom report.
"A soluble variant of ST2 (sST2) acts as a decoy receptor to regulate the activity of IL-33. In...
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