Sex Hormones
New Sex Hormones Data Have Been Reported by Investigators at Mayo Clinic
Published in Women's Health Weekly, February 9th, 2012
2012 FEB 9 -- According to the authors of recent research from Rochester, Minnesota, "In the bone marrow cavity, adipocyte numbers increase, whereas osteoblast progenitor numbers decrease with aging. Because adipocytes and osteoblasts share a common progenitor, it is possible that this shift is due to an increase in adipocyte-lineage cells at the expense of osteoblast-lineage commitment."
"Estrogens inhibit adipocyte differentiation, and in both men and women, circulating estrogens correlate with bone loss with aging. In bone cells, estrogens stimulate expression of TGF-beta and suppress mesenchymal cell adipogenesis. Using a tripotential mesenchymal cell...
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