Breast Cancer

New member of the breast-cancer gene network found by Penn-led team

Published in Women's Health Weekly, March 8th, 2012

2012 MAR 8 -- PHILADELPHIA - The infamous BRCA genes do not act alone in causing cancer; there is a molecular syndicate at work preventing the way cells normally repair breaks in DNA that is at the root of breast cancer. But finding all of the BRCA molecular collaborators has been elusive.

Researchers at the Perelman School of Medicine at the University of Pennsylvania and the University of Oulu, Finland, published their discovery of a mutation in the Abraxas gene, which interacts with the well-known breast-cancer gene BRCA1, in Science Translational Medicine this week.

The mutation affects the ability of the Abraxas protein to enter the...

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Source: Women's Health Weekly (2012-03-08)

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