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Breast Cancer

'Obscurins' in breast tissue may help physicians predict and detect breast cancer

Published in Women's Health Weekly, April 5th, 2012

2012 APR 5 -- Bethesda, MD-A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the University of Maryland, explain how proteins, called "obscurins," once believed to only be in muscle cells, act as "tumor suppressor genes" in the breast. When their expression is lost, or their genes mutated in epithelial cells of the breast, cancer develops. It promises to tell physicians how breast cancer develops and/or how likely it is.

"Our studies on the role of obscurins in the...

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