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Ovarian Cancer

Studies from Jichi Medical University Have Provided New Data on Ovarian Cancer

Published in Women's Health Weekly, April 12th, 2012

2012 APR 12 -- Researchers detail in "Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations," new data in Ovarian Cancer. "The purpose of this study was to explore the possibility of targeted molecular therapy with anti-epidermal growth factor receptor (anti-EGFR) antibody (cetuximab) for the treatment of mucinous ovarian carcinoma. We analyzed EGFR protein expression and KRAS gene mutations in 5 mucinous ovarian carcinoma cell lines RMUG-L, RMUG-S, MN-1, OMC-1 and MCAS and evaluated the in vitro and in vivo effects of cetuximab on each," investigators in Tochigi, Japan report.

"EGFR expression was...

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