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World Disease Weekly

Susan Hasty, Publisher
Table of Contents . . . November 23rd, 2004
Non-Subscriber - Summaries Only
Related Areas: Other Issues in World Disease Weekly | Other Publications

Acute Radiation Syndrome - Acute radiation syndrome therapeutics manufacturer to respond to RFI

Arsenic Contamination - Reducing arsenic contamination often increases water-related infectious diseases

Polio - WHO network has played essential role in monitoring polio eradication effort

World Population - United Nations report says world population could be 9 billion in 2300

ADHD - Adderall XR gets 6 months pediatric exclusivity

AIDS/HIV Diagnosis - OraQuick ADVANCE rapid HIV-1/2 antibody test is sensitive and specific

AIDS/HIV Vaccine - DNA vaccine elicits efficient CD8+ T cell response to HIV epitope

AIDS/HIV Vaccine - HIV-1 protease cleavage site in human C1-inhibitor identified

AIDS/HIV Vaccine - Parenteral vaccine adjuvants promote mucosal anti-HIV immune responses

AIDS/HIV Vaccine - Poxviruses expressing HIV protein stimulate cytotoxic T-cell responses

Abortion - Abortion clinic says it will not require parental consent

Abortion - Challenge to Oklahoma's parental notification law thrown out

Acne - Laboratories develop benzoyl peroxide medications for treatment of acne

Acne - Phase II Levulan PDT clinical trial for acne

Acne - Velac NDA accepted for filing by the FDA

Acute Myelogenous Leukemia - Phenotypic karyotype markers identified in AML with t(8;21)

Addiction Medicine - Injection drug users often develop hepatitis C virus superinfections

Addiction Medicine - Program decreases stimulant use and enhances body image among female athletes

Adenovirus - Fiber protein encoded by late region of bovine adenovirus characterized

Adiposity - High abdominal-to-peripheral fat alters autonomic-circulatory control

Adiposity - Metabolic role of brown adipocyte reviewed

Adrenergic Dilation - Endothelin-1 impaired beta-adrenergic dilation of resistance coronary vessels

Adrenergic Receptors - Beta₂ -AR signaling modulates function of I_Ks channels

Adrenoceptor - Buflomedil has preferential alpha_1A -adrenoceptor antagonistic effect

Aesthetic Medicine - Cynosure offers Laser Advantage Practice Success Program

Aesthetic Medicine - FDA approves Aurora and its derivative systems for permanent hair reduction

Age-Related Macular Degeneration - Study: Patients with early AMD benefit from Phototrop

Age-Related Macular Degeneration - TTT4CNV preliminary results not statistically significant in AMD trial

Aging - Dementia, mental health not adequately addressed in assisted living facilities

Aging - Hospitalization and restricted activity can lead to disability among elderly

Aging - Study looks at events that lead to disability among the elderly

Agriculture - Researchers uncover how infections combat plant immune responses

Air Quality - Smoke-free workplace laws provide protection impossible to achieve otherwise

Alcoholism - Poor decision making doesn't derail recovering alcoholics

Allergic Rhinitis - Intranasal irradiation with XeCl UVB laser ameliorates symptoms

Allergies - New Drug Application approved for once-daily Allegra-D

Allergy Medicine - Maternal exposure to diphenhydramine delays fetal CNS, sexual development

Allergy Medicine - Regulation of IL-1 beta and its inhibitor by epithelial cells described

Alopecia - Mouse model yields gene insights

Alopecia Areata - Cyclosporin A lipid vesicles show promise for treatment

Alzheimer Disease - "Going through the motions" could better treat dementia

Alzheimer Disease - Brain protein halts Alzheimer progression

Alzheimer Disease - Loci of susceptibility to amyloid precursor protein identified

Alzheimer Disease - Neuroscientists study new type of dementia drug aimed at halting AD progression

Alzheimer Disease - New oral vaccine shows promise

Alzheimer Disease - Pharma company granted patent for statin drug treatment of Alzheimer disease

Amygdalohippocampectomy - Vasospasm rate compared in transsylvian and transcortical approach

Amyotrophic Lateral Sclerosis - Nordihydroguaiaretic acid shows promise in murine model

Amyotrophic Lateral Sclerosis - Oral presentation of VP025 delivered at Neuroscience 2004

Amyotrophic Lateral Sclerosis - Phase III trial results with Neurodex published

Anesthesia - Isoflurane has fewer systemic hemodynamic effects than nonvolatile anesthetics

Anesthesia - Sevoflurane has lesser effect on left ventricular performance

Angina - Some chest pain patients may benefit from more evaluation

Angina - Study investigates mechanisms of current inhibition by lidoflazine

Angina - Supplemental NDS for Tiazac XC accepted for review in Canada

Angina Therapy - Study of Ranexa enrolling ahead of schedule

Angiology - Findings may generate new targets for prevention, treatment of vascular diseases

Angiology - Multiphoton microscopy useful for imaging coronary artery microstructure

Angiology - No association is found between K469E polymorphism and ischemic heart disease

Angiology - Paclitaxel induces G₁ arrest in arterial smooth muscle cells

Angiology - Protease activated receptors are involved in vascular development

Angiology - Studies enable analysis of mechanical forces influence during heart development

Angiology - The use of statins is associated with a reduced risk of venous thromboembolism

Animal Models - Goat model of S. aureus infection evaluated

Anthrax - Crystal structure of Bacillus anthracis DHPS elucidated

Anthrax - U.S. to buy 75 million doses of vaccine

Anthrax Vaccine - Anthrax protective antigen predictive of serum anti-toxin activity

Anthrax Vaccine - Anthrax proteins associated with germination and outgrowth identified

Anthrax Vaccine - Grant provides $3.5 million for anthrax vaccine study

Anti-Infective Agents - Sulfamates offer promise as anti-infective/anticancer agents

Anti-Infectives - Antibiotic residues characterized in milk from Manchega ewe dairy farms

Anti-Infectives - Mechanisms of gentamicin-induced nephrotoxicity elucidated

Anti-Infectives - P-gp inhibitors can increase ocular erythromycin bioavailability

Anti-Inflammatory Agents - Resveratrol has novel nonsteroidal anti-inflammatory properties

Antiadrenergic Effects - Translocation of PKCepsilon plays an important role in the heart

Antibiotic Resistance - CY401 is active against the most resistant bacteria strain

Antibiotics - Lipopeptides are new agents for treating Gram-positive infections

Antidepressants - Inactivation of 5-HT_2C receptors augments SSRI efficacy in rats

Antidepressants - Mirtazapine-induced lymphocyte gene expression altered in Alzheimer patients

Antiretroviral Therapy - Antiretroviral CSF penetration improves cognitive disorders in HIV infection

Antiviral Drug Development - Rab9 identified as a novel antiviral drug target

Apoptosis - Capillin induces apoptosis in tumor cells

Apoptosis - HTLV-1 Tax oncogene causes tumorigenesis

Arteriogenesis - Resident tissue precursors initiate vascularization

Arthritis - Alendronate and estrogen could slow progression of osteoarthritis

Arthritis - Effects of rheumatoid arthritis and age on autonomic CV reflex are not additive

Arthritis - Irregular menstrual cycles linked to increased risk of disease

Arthritis - Melittin in bee venom blocks inflammation

Arthritis - Study finds expensive medications being used by youngest patients

Arthritis Therapy - Effects of iNOS inhibition on collagen-induced arthritis described

Artificial Blood - Loyola joins artificial blood study; patients to be tested without permission

Assisted Living - Assisted living in the U.S. costs an average of $2,524 per month

Assisted Reproduction - Mouse oocytes useful for evaluating oocyte-activating capacity of human sperm

Assisted Reproduction - Term singleton birth rate per started IVF course proposed as success end-point

Assisted Reproduction - Winston-Salem woman gives birth to quintuplets

Asthma - Approvable letter issued by FDA for Alvesco (ciclesonide)

Asthma - Electronic records may improve care for children with asthma

Asthma - Melatonin improved sleep in small study of asthmatic women

Asthma - Melatonin improves sleep in asthmatics

Asthma - Pharma company's Aridol phase III trial achieved endpoints

Asthma Therapy - Anti-IgE antibody omalizumab relieves airway inflammation in asthma

Astronomy - A source of cosmic rays discovered

Atherosclerosis - Chronic infection plays a role in the pathogenesis of atherosclerosis

Atherosclerosis - Higher OPG levels may be associated with IMT in postmenopausal women

Atherosclerosis - Low BMD is related to increased risk of echogenic carotid artery plaques

Atherosclerosis - Nuclear medicine diagnostic techniques reviewed

Attention Deficit Hyperactivity Disorder - U.S. FDA approves use of CONCERTA 72 mg for treatment of ADHD

Autoimmune Disease - Single nucleotide polymorphisms lead disease susceptibility

Avian Influenza - WHO: Ducks may infect humans with bird flu

Awards - Genomic institute executive members Fraser and Salzberg honored as AAAS Fellows

Awards - Human Genome Project scientist at Sanger Institute receives top science award

Awards - Invacare Corporation's 2003 annual report honored by NAIC

Awards - Pharmacy benefit manager among Utah's Top Revenue Growth companies

Awards - Pinnacle award for innovation, technology won by Pennsylvania university

Awards - Southern Methodist University receives 'Champions in Health' award

Back Pain - Center for artificial disc replacement surgery to open in Texas

Bacterial Dysentery - Taiwan warns travelers to be on alert against bacterial dysentery

Bacterial Vaginosis - Bacteria more likely to develop resistance to clindamycin than metronidazole

Bacteriology - Coryneform isolates identified as Rothia and Corynebacterium

Bacteriology Vaccine - IgG2 recognizing phosphorylcholine protects against bacterial pathogens

Balance and Fall Prevention - Ingen Technologies teams with SPORTKAT to enhance Secure Balance program

Bausch & Lomb - Cataract surgeons get more flexibility with Millennium Advanced Flow System

Bifidobacterium Lactis - Potential role seen for Bifidobacterium in the intestinal degradation of oxalate

Biliary Obstruction - NIH grant to research development of coating to prevent biliary stent occlusion

Biochemical Markers - Clinical use of markers will sharpen understanding of heart failure

Bioengineering - Laser spray dissociates non-covalent bonds without harming molecular subunits

Biotechnology - Bonding of glass microfluidic chips at room temperature achieved

Biotechnology - Drug electrophoresis systems with contactless conductivity detection devised

Biotechnology - Microfluidic T-form mixer using switching electroosmotic flow devised

Biotmaterials - Antibacterial bioactive glass developed for head and neck structural defects

Birth Defects - Physical exposures during pregnancy not linked to congenital heart defects

Bladder Cancer - Study shows COMBIDEX aids in diagnosis of metastatic lymph nodes

Bladder Function - Viscoelastic response changes in urinary bladder after spinal cord injury

Blindness - Researchers within sight of a breakthrough on blindness

Blood Banking - Diagnostic company launches blood bank educational initiative

Blood Banking - SC refrigeration is simple option for autotransplants within few days of harvest

Body Image Disturbance - Weight training may be effective for body-imaged-disturbed college women

Bone Marrow Transplantation - Bone marrow found for woman seeking South Asian donors

Bone Marrow Transplantation - Patients with impaired LV ejection fraction can achieve long-term survival

Bone Marrow Transplantation - Psychosocial/behavioral variables do not effect 1-year survival after BMT

Botulism - Eighty percent of botulism outbreaks attributed to home-preserved vegetables

Bovine Spongiform Encephalopathy - Scientists raise concerns about second wave of 'mad cow' prion infection

Bovine Viral Diarrhea - Bovine viral diarrhea virus with deletions protects calves

Brain Tumors - The tyrosine kinase inhibitor ZD6474 strikes down glioma growth in xenografts

Breast Cancer - Company ships first dedicated breast MRI system outside the U.S.

Breast Cancer - Disease and therapy can result in thoracic changes

Breast Cancer - Fruits, vegetables may decrease some women's risk of ER-positive cancer

Breast Cancer - Higher serum relaxin levels associated with metastatic disease

Breast Cancer - Meta-analysis finds glutathione S-transferase M1 status a potential risk factor

Breast Cancer - More testing methods OK'd to select patients who may benefit from Herceptin

Breast Cancer - New protein associated with aggressiveness in breast and ovarian cancer

Breast Cancer - New technique detects microcalcifications more reliably

Breast Cancer - Parity-induced mammary epithelial cells promote tumor growth in transgenic mice

Breast Cancer - Study: "Substantial" genetic influence on dysplastic breast glandular tissue

Breast Cancer - U.S. FDA clears diagnostic viewing of digital mammography

Breast Cancer - Wife of Senator Edwards undergoes tests to determine breast cancer treatment

Breast Cancer - Women put bra art on display to promote health

Breast Cancer Therapy - ¹¹¹In-DTPA-trastuzumab suitable for clinical use

Breast Cancer Therapy - Celecoxib and alpha-TEA shows promise as combination therapy

Breast Implants - Gel-filled breast implants to be marketed in Australia

Business & Finance - BioSciences company releases financial results

Business & Finance - Bioanalytical measurement system developer releases product, financial results

Business & Finance - Biopharmaceutical company announces third quarter 2004 results

Business & Finance - Biotechnology company receives $5 million financial commitment

Business & Finance - CollaGenex Pharmaceuticals agrees to sell U.K. and European dental assets

Business & Finance - Company announces sale of BioSepra process chromatography

Business & Finance - Company reports Q3 results, provides initial FDA guidance on DX-88 Program

Business & Finance - Dermatology-focused pharma reports Q3 earnings per share of $0.10

Business & Finance - Device company's Q2 revenue rises 10%; names VP engineering

Business & Finance - Disposable products producer reports financial results, acquisition

Business & Finance - Information technology company announces financial results

Business & Finance - Maker of Zicam products reports third quarter results

Business & Finance - Medical billing and transcription company closes $1.6 million in financing

Business & Finance - Medical device company reports financial results

Business & Finance - Medical device company reports third quarter 2004 financial results

Business & Finance - Medical technology company reports financial results

Business & Finance - Online prescription drug company reports financial results

Business & Finance - Orthopedic products company releases financial results

Business & Finance - Personal care products company announces 13% year-over-year revenue growth

Business & Finance - Pharma company announces 9 month financial results

Business & Finance - Pharma company announces financial results

Business & Finance - Pharma company announces profit increase of 43%

Business & Finance - Pharma company reports improved financial results

Business & Finance - Pharma company reports third quarter 2004 financial results

Business & Finance - Pharmaceutical company reports financial results

Business & Finance - Pharmaceutical company reports loss of $0.41 per share

Business & Finance - Pharmaceutical company to trade on Warsaw Stock Exchange

Business & Finance - Pharmaceutical firm reports loss of $0.32 per share, provides pipeline update

Business & Finance - Pharmaceutical updates divestiture process, clinical development projects

Business & Finance - Pharmaceuticals company completes $16 million venture capital financing

Business & Finance - Schwarz reports decline in sales, positive research and development

Business & Finance - Software and services company announces financial results, new contract

Business & Finance - Stretta System maker wins continued listing on the Nasdaq SmallCap Market

Business & Finance - Vitamin maker commences Dutch auction tender offer

Business Update - Bioinformatics solutions provider appoints Elchrom Scientific as distributor

Business Update - Biopharmaceutical company launches new phosphoprotein screening service

Business Update - Biotech applies for ASE listing, updates status of infectious diseases research

Business Update - Cardinal Health announces lower earnings

Business Update - Cigna profit soars 64% on unit sale, health-segment growth

Business Update - Company opens nucleic acid amplification testing laboratory

Business Update - Contract pharmaceutical manufacturer completes $1.4M expansion

Business Update - Crown Medical Systems retains MCC Financial Group for IR support

Business Update - Curative Health Services opens new Critical Care Systems' branch locations

Business Update - DePuy Spine acquires spinal assets of Micomed Ortho

Business Update - Dermatology company completes sale of assets to ICOS Corporation

Business Update - Direct-to-consumer drug advertising survey shows fewer people act due to ads

Business Update - EAU retains Strategic Growth International for investor relations

Business Update - Elekta expands open systems commitment with new sales consulting agreement

Business Update - Fish oil producer announces completion of health and science center

Business Update - Four board members named and new center opened by cancer support group

Business Update - Generic drug company signs supply agreement

Business Update - GlaxoSmithKline acquires exclusive worldwide rights to Albugon

Business Update - Hand-held disease-monitoring product provider receives ISO-certification

Business Update - Healthcare marketing company to manage launch of extended-release expectorant

Business Update - Healthnotes releases Version 7.9 of touchscreen kiosk software

Business Update - IPC enters agreement with San Antonio-based Metropolitan Methodist Hospital

Business Update - MIS company acquires intellectual property portfolio from MIS surgery pioneer

Business Update - MedImmune eyes expansion in Frederick, Maryland

Business Update - Medical center joins growing health consortium

Business Update - Medical technology company supports events, activities for disabled employees

Business Update - Oncology IT solutions provider expands European radiation oncology business

Business Update - Pharmaceuticals firm provides business update

Business Update - Study indicates steady growth through 2008 in clinical trial management market

Business Update - Supply chain company hosts conference featuring medical technology vendors

Business Update - U.S. FDA grants 6 months additional market exclusivity to Shire's ADDERALL XR

Business Update - U.S. FDA grants Vitrase 5-year market exclusivity

Business Update - U.S. FDA selects hospital database for two drug utilization contracts

Business Update - UCB Pharma opts out of co-promotion agreement with dermatology products maker

Cancer & Fertility - Lance Armstrong's former wife summons the courage for her own race

Cancer Diagnostics - NIH grant to be used for study of ATN-161 analogs as cancer imaging agents

Cancer Genetics - BRCA1/2 tests available, but ethics, economics restrain use in France

Cancer Immunology - Phage-based microarrays useful for humoral immune analysis

Cancer Immunotherapy - Anti-ErbB2 antibody cuts off tumor growth

Cancer Proteomics - Cancer-altered metabolism linked to cytochrome c oxidase subunit variation

Cancer Research - Cancer-killing activity of gene-based INGN 241 therapy in tumors identified

Cancer Research - Drug used to stabilize vessels, block cancer cells from leaving bloodstream

Cancer Research - Pharma companies move to next phase of collaboration on cancer targets

Cancer Research - Pharma company provides Tarvacin IND update

Cancer Research - Study sheds light on how poxviruses can jump from species to species

Cancer Screening - EUROGIN data documents cost-effectiveness of DNAwithPap Test

Cancer Therapy - Anticancer agents activate antiangiogenic gene therapy

Cancer Therapy - Biomarkers of effective Herceptin therapy identified

Cancer Therapy - Biopharmaceutical, MGI Pharma announce Dacogen MAA accepted for review by EMEA

Cancer Therapy - Boston study shows experimental cancer drugs getting safer

Cancer Therapy - Company initiates phase I clinical trial for XL999

Cancer Therapy - Data: Provenge extends survival in patients with advanced prostate cancer

Cancer Therapy - Engineered stem cells can home in on tumors and deliver drug payload in mice

Cancer Therapy - Fewer risks seen for patients participating in early-phase cancer drug trials

Cancer Therapy - Genomic response of fission yeast to cisplatin determined

Cancer Therapy - Licensing agreement forged to market aniemetic for chemotherapy patients

Cancer Therapy - Patent granted for production and processing of the reovirus

Cancer Therapy - Pharma company announces completion of recruitment for skin tumor trial

Cancer Therapy - QUADRAMET data presented at Prostate Cancer Foundation scientific retreat

Cancer Therapy - Scientists find key to unlock body's own cancer defense

Cancer Therapy - Stem cells ferry concentrated anticancer drug to tumors

Cancer Therapy - Substance may improve cancer immune therapy, vaccines

Cancer Vaccine - Biotech receives patent allowance for nonlethal hemocyanin extraction method

Cancer Vaccine - Control parameters for dendritic cell-T cell interaction determined

Cancer Vaccine - Heat shock protein gp96 elicits anti-tumor CD8 T cell cytotoxicity

Cancer Vaccine - OX40L exhibits anti-tumor therapeutic efficacy in murine tumor model

Caprine Arthritis Encephalitis Virus - Caprine arthritis encephalitis virus isolated from sheep during epidemic

Carcinogenicity - Assessing carcinogenic risk in human drug development reviewed

Cardiac Arrest - Morphological changes in neurons may be associated with cognitive impairment

Cardiac Fibrosis - The heart is sensitive to effects of excess urokinase plasminogen activator

Cardiac Grafts - Study investigated preexisting apoptosis in donor hearts

Cardiac Hypertrophy - Intronic activator element plays a role in cardiac hypertrophy

Cardiac Hypertrophy - NF-kappaB could be a target for inhibiting development of cardiac hypertrophy

Cardiac Imaging - U.S. patent for new cardiac magnetic resonance imaging technology granted

Cardiac Surgery - Blood flow monitoring system could reduce risks during surgery

Cardiology - A new thrombosis and angiogenesis signaling pathway has diagnostic value

Cardiology - Antiplatelet agent slated for new Phase III trial

Cardiology - Authors advocate describing heart components as seen in the anatomical position

Cardiology - Beta-adrenoceptor-induced hypertrophy led to impairment of cardiac baroreflex

Cardiology - COOH-terminal truncation enhance thin filament activation in myocardium

Cardiology - Calreticulin and endoplasmic reticulum may play important roles in development

Cardiology - Disturbances in protein phosphatases may cause or aggravate cardiac diseases

Cardiology - Kensey Nash provides update on TriActiv System FDA approval status

Cardiology - Major effect of enalapril is mediated by increased density of vessels

Cardiology - Newly detected hhLIM protein is implicated in heart hypertrophy

Cardiology - Process of cardiac valve development elucidated

Cardiology - Results reinforce evidence for heterogeneity of the Na⁺-K⁺-ATPase

Cardiology - Review focuses on pathways involved in regulating myocardial energy metabolism

Cardiology - Role of cardiac myosin binding protein-C on myocardial stiffness was examined

Cardiology - Six U.S. medical centers using NMR spectroscopy to manage heart disease

Cardiology - Slow skeletal troponin T gene may contribute to myocardial dysfunction

Cardiology - Small increases in central venous pressure decrease baroreflex control

Cardiology - Sphincter-like action of the mitral annulus may facilitate ventricular filling

Cardiology - Study examined the effects of low Na⁺ on isolated cardiomyocytes

Cardiology - Study examines the role of melanin-concentrating hormone in energy balance

Cardiology - The evolutionary history of angiotensinogen suggests nonrandom gene mutations

Cardiology - Troponin T binding regions can alter sarcomeric performance

Cardiology - U.S. FDA clears Breva Surgical Probe for treatment of cardiac arrhythmias

Cardiology - Uncouplers blocked ventricular tachycardia induced by burst pacing

Cardiomyopathy - Animal model systems have increased knowledge of myopathic muscle physiology

Cardiomyopathy - KDEL receptor disturbs endoplasmic reticulum quality control

Cardiomyopathy - Mutations in cell adhesion genes provide basis for improved diagnosis

Cardiopulmonary Resuscitation - New recommendations for single-rescuer CPR should be considered

Cardiorespiratory Neurons - Method solves many problems in studying cardiorespiratory neurons

Cardiovascular Devices - Long-term outcome of coronary multilink stents determined

Cardiovascular Disease - Biosciences company launches trial for mild to moderate congestive heart failure

Cardiovascular Disease - Health services company works to detect cardiac arrhythmias in astronauts

Cardiovascular Disease - Medical diagnostic equipment company collaborates on cardiovascular study

Cardiovascular Disease - Study: Diabetes drug reduces artery reclogging

Cardiovascular Disease - Trial shows metoprolol CR/XL does not impair glucose and insulin levels

Cardiovascular Responses - Electroacupuncture leads to point-specific effects on CV reflex responses

Carotid Stent - Company begins enrollment in new study of carotid stenting

Cataracts - Gene mutations responsible for childhood cataracts discovered

Celiac Disease - New study looks at patients diagnosed over span of 52 years

Cell Biology - 3D flow control concept devised for single-cell microchip experiments

Cell Biology - Heparan sulfate proteoglycans tether angiopoietin-3 to the cell surface

Cell Biology - Initial sensor for p53 tumor-suppressing pathway identified

Cell Biology - Ninein regulates microtubule nucleation

Central Nervous System Disorders - Pharmaceutical company acquires new compound to treat insomnia

Cerebrovascular Disease - New approaches to common methods depict vascular morphology in the brain

Cervical Cancer - Investigational vaccine reduces risk of HPV-related cervical cancer

Cervical Cancer - Irinotecan plus nedaplatin with rhG-CSF shows therapeutic promise

Cervical Cancer - Plasma HPV DNA may be useful to monitor therapy and disease progression

Cervical Cancer - SELDI MS plus proteomics scoring distinguishes cancerous from normal cervix

Cervical Cancer - Study: No justification for colposcopy in screening of young women

Chemotherapy - APE/redox effector factor protein is a target for overcoming drug resistance

Chest Pain - Women's anxiety sensitivity related to pain response, interpretative bias

Chickenpox Vaccine - Varicella screening in adolescents is cost-effective

Chlamydia Pneumoniae Vaccine - DNA vaccine plus booster protects against Chlamydia pneumoniae

Cholesterol - Data demonstrates the efficacy of CRESTOR in treating elevated cholesterol

Cholesterol - Skin sterol test for cholesterol provides information about heart disease risk

Cholesterol - Trial showed VYTORIN superior to Lipitor at lowering bad cholesterol

Chronic Hepatitis B - Biochemical flares arise in patients with hepatitis B virus mutants

Chronic Hepatitis B - Hepatitis B virus DNA in the liver correlates with extent of liver injury

Chronic Hepatitis C - Viral load and liver enzyme levels fluctuate in hepatitis C-infected patients

Chronic Liver Disease - Biochemical tests could supplant liver biopsies for diagnosing liver fibrosis

Chronic Lymphocytic Leukemia - Utility of antibody-based CLL treatments reviewed

Chronic Obstructive Pulmonary Disease - Company updates clinical program for chronic obstructive pulmonary disease drug

Chronic Obstructive Pulmonary Disease - Interval exercise should provide rehabilitative benefits for COPD patients

Chronic Obstructive Pulmonary Disease - Theophylline may restore steroid responsiveness in COPD patients

Chronic Wasting Disease - Minnesota to conduct more testing for chronic wasting disease

Climate Change - New tool to help fight global warming developed

Clinical Trials - Integrated technology platform for clinical studies presented at PARCS meeting

Clinical Trials - Investigational new drug application for cancer drug approved by U.S. FDA

Clinical Trials - Once attracted, U.S. minority populations tend to participate in studies

Clinical Trials - Phase 3b trial in IGF-1 deficiency short stature initiated

Cloning - Companies partner to bring new product to clone archiving market

Cognitive Dysfunction - Effect of beta-amyloid prevented in cognitive dysfunction model

Collaboration - Contract awarded for safety IV catheter device

Collaborations - Aetna, Priority Healthcare announce location of new pharmacy partnership

Collaborations - Alaris Medical Systems extends contract with MedAssets

Collaborations - Allscripts signs TouchWorks agreements for electronic medical records

Collaborations - Amedisys selects MedeFinance business intelligence solution

Collaborations - ComGenex, partner, expand their drug-discovery collaboration

Collaborations - Companies announce collaboration for novel TFPI peptides

Collaborations - Companies collaborate on oncology market research

Collaborations - Deal signed with Tulane for potential anticancer agents

Collaborations - Diabetic limb ischemia clinical trial agreement signed

Collaborations - Drug discovery collaboration success achieved with Schering AG

Collaborations - Drug discovery company, Novo Nordisk collaborate on TTP translational technology

Collaborations - Equipment company opens biomarker research facility with Massachusetts General

Collaborations - Firm retains pharmaceutical special projects group to develop Phenserine

Collaborations - Licensing deal signed for rapid microbial detection

Collaborations - Milestone achieved in discovery of compound for cardiovascular application

Collaborations - Milestone reached in a research collaboration with Novo Nordisk

Collaborations - Nutraceuticals company signs distribution deal with PIVEG

Collaborations - Pharma companies sign drug development, distribution agreement

Collaborations - Research agreement signed with Merck for RNAi-modified mice

Collaborations - Strategic alliance formed for metabolic disease drug development

Collaborations - Two Texas entities launch joint venture to develop spine centers

Collaborations - ddRNAi license granted to Artemis Pharmaceuticals

Colon Cancer - Brochure helps explain treatments for colorectal cancer

Colon Cancer - Capsule endoscopy aids in detection of small bowel tumors

Colon Cancer - Enhanced aspirin holds promise as colon cancer preventive agent

Colon Cancer - MOK direct target gene for Cdx2; may be involved in intestinal epithelial cells

Colon Cancer - Model suggests higher mortality for virtual colonoscopy

Colon Cancer - Novel Bcl-2 family gene associated with progression of colon cancer

Colon Cancer - Obese women face higher risk of colorectal tumors

Colon Cancer - Smoking increases risk of colon polyps

Colon Cancer - Study reveals genetic link to colon cancer

Colon Cancer - Targeted therapy + efficient chemotherapy increases colorectal cancer survival

Colorectal Cancer - Early screening important for African Americans, Hispanics

Colorectal Cancer - Excessive alcohol intake plus low folate increase risk of colorectal cancer

Colorectal Cancer - Obese women face higher risk for colorectal neoplasia than men

Colorectal Cancer - Positive opinion granted in Europe for metastatic colorectal cancer therapy

Colorectal Cancer - Screening for variety of genes could determine bowel cancer risk

Complementary & Alternative Medicine - Guided imagery appears to produce relaxation and improve memory

Complementary & Alternative Medicine - Studies suggest green tea/tea polyphenols lower cancer risk/inhibits tumors

Complementary and Alternative Medicine - Ancient remedies may hold clues for future medical breakthroughs

Complementary and Alternative Medicine - Black cohosh may trigger autoimmune hepatitis

Complementary and Alternative Medicine - Products suspected of containing Aristolochia or Asarum analyzed

Complementary and Alternative Medicine - Researchers: Religious faith shortens hospital stays, aids recovery

Complementary and Alternative Medicine - Ya-hom inhibits histamine effects on stomach acid and pepsin

Congenital Heart Defects - Team discovers possible genetic mechanism behind heart defects

Congenital Hypothyroidism - High prevalence of parental consanguinity in infants with permanent CH

Congestive Heart Failure - Decrease in expression of LZ⁺ MYPT1 isoform causes NO-mediated relaxation

Congestive Heart Failure - Fat buildup found in hearts of obese or diabetic heart failure patients

Connective Tissue Disease - Novel variants of the ADAMTS2 gene mark Ehlers-Danlos syndrome Type VIIC

Constipation - Fiber and water help holiday travelers' digestive health

Contraception - Global pharmaceutical gets U.S. FDA approval for generic contraceptive

Contraception - Heat shock protein acts as efficient carrier for GnRH vaccine

Coronary Artery - Coronary artery must be treated as a composite, nonisotropic body

Coronary Artery Bypass Grafting - Post-CABG drop in heart rate variability is reversible

Coronary Artery Disease - Enrollment initiated in ARRIVE 2 drug-eluting stent registry

Correctional Medicine - New Alabama healthcare chief says system needs funds, not Band-Aids

Craniofacial Surgery - Calcigen S bone void filler is effective tobramycin vehicle

Craniofacial Surgery - Novel technique developed for surgical treatment of cystic jaw disease

Creutzfeldt-Jakob Disease - A novel mutation in the human prion gene has been discovered in China

Creutzfeldt-Jakob Disease - Scientists raise concerns about second wave of "mad cow" prion infection

Critical Care - American College of Chest Physicians forms Critical Care Institute

Critical Care Medicine - Non-invasive ventilation use in surgical patients characterized

Crohn Disease - Gene mutations increase risk for surgery in children with bowel disease

Cytomegalovirus - Human cytomegalovirus-induced host cell enlargement is iron dependent

DNA Methylation - Inefficient 3-methylthymine repair causes steady state mutant accrual

DNA Research - Automated scoring procedure developed for micronucleus test

DNA Research - IPP reported to inhibit oxidative DNA damage

DNA Research - Life sciences company introduces plasmid DNA isolation method

DNA Research - Microfluidic system developed for large DNA molecule arrays

DNA Research - Role of XPC protein in cellular response to cisplatin treatment clarified

DNA Vaccine - Serine/threonine kinase modulates bacteria-induced IL-12 production

Dendritic Cell Vaccine - Poly(lactic-co-glycolic acid) enhances maturation of dendritic cells

Dengue Vaccine - Dengue infection enhanced by sera from dengue-vaccinated children

Dental Health - Biotechnology company announces that IND for Oragenics' remains on hold

Dental Health - Dental company launches tooth whitening system

Dental Health - Texas publication selects super dentists for 2004

Dental Implants - FDA approval granted for Silhouette Laser-Lok dental implants

Depression - Electroconvulsive therapy improves mood, quality of life

Depression - FDA approval granted for citalopram hydrobromide tablets

Dermatology - Apaf-1 may sensitize human cutaneous melanoma to cancer therapy

Dermatology - Cells expressing nestin-driven marker model early skin angiogenesis

Dermatology - Medical products supplier begins developing dermal filler product

Developmental Biology - Enzyme Baf60c required for heart formation

Developmental Biology - Jellyfish possess homologues of human vascular endothelial growth factor

Diabetes - Partnership forged to uncover genetic basis for type 2 diabetes

Diabetes - Pharma company terminates further development of Balaglitazone -DRF 2593

Diabetes Complications - Intracorporal hSlo cDNA injections revive erectile capacity in diabetic rats

Diabetes Education - Patti LaBelle encourages Americans to manage diabetes 365 days a year

Diabetes Pathogenesis - Pathogenesis of type 2 diabetes reviewed

Diabetes Pathogenesis - Phosphatidylinositol 4,5-bisphosphate prevents insulin resistance

Diabetes Prevention - Case analysis of legitimizing diabetes as a community health issue presented

Diabetes Quality of Life - Diabetes compromises quality of life among Americans

Diabetes Risk Factor - Agent Orange exposure in Vietnam veterans promotes insulin resistance

Diabetes Survival and Mortality - Blood pressure not linked to mortality of diabetic renal transplant patients

Diabetes Therapy - FDA grants approval for generic Glucophage XR

Diabetes Therapy - Hybrid pancreatic tissue substitute developed

Diabetes Therapy - Insulin therapy in type 2 diabetes reviewed

Diabetes Therapy - Insulin-like growth factor complex improves insulin sensitivity in diabetes

Diabetes Therapy - Pioglitazone improves insulin sensitivity in type 2 diabetic patients

Diabetes Therapy - Reduction in free fatty acid level improves insulin action in type 2 diabetes

Diabetic Nephropathy - Nephropathy in diabetic fat rat linked to oxidative and nitrosative stress

Diabetic Retinopathy - Nitric oxide and cyclooxygenase-2 interact to generate diabetic eye disease

Diagnostics - A new assay improves the timeliness and sensitivity of hepatitis C detection

Diagnostics - Archival cytologic samples suitable for PCR testing

Diagnostics - CADstream Breast MRI gets ISO 13485:2003 and CE Marking certifications

Diagnostics - Core antigen assay can't confirm active hepatitis C virus infection

Diagnostics - Counting immunoassay detects hepatitis markers in whole-blood samples

Diagnostics - Diagnostic kit maker receives approval to export Vscan test kits from China

Diagnostics - Diagnostics company donates rapid HIV tests in China

Diagnostics - Lab-based oral fluid drug testing device introduced

Diagnostics - Nanogen introduces diagnostic testing and diagnostic development platform

Diagnostics - Novel method detects/quantitates hemoglobin-based oxygen carriers in plasma

Diagnostics - Routine use of chip-mediated diagnostic techniques still in question

Diagnostics - Systems biology approach may bring new age of predictive, preventive medicine

Diet and Nutrition - Association between energy intake and mortality in men reported

Diet and Nutrition - Intragastric gelation can increase feeling of satiety in humans

Diet and Nutrition - Modified starch lowers glycemic response due to reduced absorption

Diet and Nutrition - Palatability based on hedonic aspects of eating rather than nutritional need

Dietary Supplements - Chewable multivitamin introduced

Disease Associations - Neurodegenerative disorders associated with diabetes reviewed

Disease Associations - Paraoxonase 1 gene changes are not Parkinson disease risk factors in Finland

Disease Associations - Tooth patterning, enamel formation affected by TNF receptor Edar

Disease Management - Molina Healthcare enhances disease management program

Disease Prevention - Estradiol may be beneficial in preventing cardiovascular disease

Disease Prevention - Malawi: Project encourages female condom use to prevent HIV transmission

Domestic Violence - Blue Shield of California Foundation awards $6.7M to 304 organizations

Down Syndrome - Gene signatures of transient and acute megakaryoblastic leukemia identified

Down Syndrome - Retardation treatment in the womb may one day be possible

Drug Delivery - Drug-loaded micelles reported cytotoxic in human breast cancer cells

Drug Delivery - Initial human clinical results of transdermal vaccination study 'promising'

Drug Delivery - Insulin supplier to invest $100 million in North Carolina facility expansion

Drug Delivery - Maker of drug delivery devices announces agreement with GlaxoSmithKline

Drug Delivery - Microemulsion systems show promise for transdermal triptolide delivery

Drug Delivery - NIPAM copolymers useful for liposome temperature sensitization

Drug Delivery - New measures aim to improve drug safety

Drug Delivery - Performance of novel budesonide dry powder inhalers compared

Drug Delivery - Starch acetate microparticles may deliver drug to RPE

Drug Delivery - U.S. FDA approves new oral solution of LEVAQUIN

Drug Development - Anti-CEA antibody T84.66 humanized

Drug Development - Cancer-focused company reports atomic structure of c-KIT in complex with Gleevec

Drug Development - Drug development company reports small molecule Hedgehog agonists results

Drug Development - Evogene to evaluate plant-based production of therapeutic protein candidates

Drug Development - FXR may be a target for drugs to treat dyslipidemia and cholestasis

Drug Development - Light-directed gene delivery shows promise for therapeutic use

Drug Development - New reagents enable efficient detection of known human and mouse miRNAs

Drug Development - Novel quinolones have promising antitumor activity

Drug Development - Novel screening method yields acetylcholinesterase inhibitors

Drug Development - Novel substrate phage display screens for treatment-induced proteomic changes

Drug Development - Screening assay devised for inhibitors of mitotic kinesin Eg5

Drug Development - Selective heparanase inhibitors halt cancer metastasis

Drug Development - TX-1898 is an antiangiogenic hypoxic cell radiosensitizer

Drug Development - Ultrafast analytical method developed for high-throughput parallel synthesis

Drug Discovery - Drug discovery company enters distribution agreement in Japan with GE Healthcare

Drug Monitoring - High-sensitivity method useful in drug monitoring, interaction studies

Drug Therapy - Inhibiting protease action is expected to be part of heart function improvement

Drug-Resistant Enterococcus - Vancomycin-resistant E. facecalis disseminated between hospitals 100 km apart

Drug-Resistant Staphylococcus Aureus - Molecular monitoring determines nosocomial dissemination of MSRA

Dyslipidemia - Biotech provides nonhuman research materials to develop HDL therapy

Edwardsiella Vaccine - Membrane protein of Edwardsiella tarda is vaccine candidate

Electronic Medical Records - Glendora Digestive Disease Institute selects EMR system from Prime Clinical

Electronic Medical Records - Information technology company extends product line, announces alliance

Electronic Medical Records - Medical management solutions provider receives Microsoft server certification

Emergency Medicine - Madrid bombing yields lessons in trauma care

Emesis - Study suggests antiemetic drug prevents post-op vomiting in children under 2

Emphysema - Alpha1-proteinase inhibitor treatment may improve hereditary emphysema outcome

Endocrinology - Combined oral contraceptives affect activated protein C resistance

Endocrinology - Human islets contain tissue-restricted transcripts

Endocrinology - Increased pulsatile GnRH levels may be involved in menopausal symptoms

Endocrinology - Technique needed to measure free testosterone levels in the female range

Endocrinology - Thyroid hormone and its analogs modulate the expression of cardiomyocyte genes

Endometrial Cancer - Height, obesity, and activity level associated with cancer risk

Endometriosis - Menstrual effluent alters proteins involved in mesothelial cell transitions

Endothelial Dysfunction - Study indicates need to integrate alternative medicine practice with research

Enterococcal Infections - Collaboration to develop therapeutic products for enterococcal infections

Environmental Health - A long wait for Love Canal health study that promises no answers

Environmental Health - Air pollution may prevent cardiovascular fitness from exercise

Environmental Health - Health investigators link North Carolina E. coli cases

Environmental Health - Survey reports high levels of lead in water at some NY schools, more possible

Environmental Health - West Virginia residents file lawsuit over chemical leak

Environmental Health - Workers sickened at home and garden warehouse

Environmental Toxins - Flame retardants cause brain damage in young mice

Environmental Toxins - Real super-bugs can save the planet

Enzymology - Genetic defects in acyl-CoA dehydrogenases influence enzymatic stability

Enzymology - MEK inhibitors impair insulin-stimulated glucose uptake in 3T3-L1 adipocytes

Enzymology - Novel immunoassay facilitates cytochrome P450 quantification

Eosinophilic Esophagitis - Pittsburgh region becoming hotspot of new disease

Epidemiology - Human disease outbreaks are bioindicators of ecologic well-being

Epidemiology - The minimum spanning tree model tracks the source of hepatitis C outbreaks

Epigenetics - Genetic double-agents unmasked

Epilepsy - Spike rates may help assess outcome of vagus nerve stimulation

Epstein-Barr Virus - Rheumatoid factors induce signaling from B cells and lead to EBV activation

Erectile Dysfunction - Drug delivery company announced acceptance of patent application for Alprox-TD

Erectile Dysfunction - Early VEGF supplementation ameliorates cavernosal ischemia in rabbit models

Escherichia Coli - Multi-parameter flow cytometry used in E. coli study

Esophageal Cancer - Studies link obesity to increased frequency of heartburn symptoms

Evolutionary Biology - Fossil fish sniffs out answer to nostril paradox

Exercise - Tired of Tae Bo? Health clubs now offering belly dancing

Eye Care - Rostock Cornea Module for confocal laser microscope receives FDA clearance

Eye Health - Research shows NearVisionSM CK is nation's leading nonlaser refractive procedure

Eye Health - U.S. and Russia form Inter-Regional Association of Ophthalmology

Facilities - Humana adds Sonora Quest Laboratories for outpatient laboratory services

Female Sexual Arousal Disorder - Phase II clinical trial data presented on topical alprostadil

Fibrosarcoma - Tumor reoxygenation compared after carbon-ion and X-ray irradiation

Finance - American Mobile Dental Corporation begins trading under symbol AMBD

Finance - American Shared Hospital Services reports 3% increase in revenue

Finance - American Stock Exchange lists stock of pharmaceutical firm

Finance - Antibody maker reports loss $0.48 per share

Finance - ArQule announces third quarter earnings

Finance - Automated urinalysis technology company expects revenue growth of 30-35%

Finance - Biopharmaceutical company reports third quarter financial results

Finance - Biopharmaceutical company reports third quarter increase of $1M

Finance - Biopharmaceutical firm reports loss of $0.54 per share

Finance - Biotech Holdings private placement funding to be applied to diabetes drug launch

Finance - Biotech company initiates IPO of 5,000,000 shares of stock at $6 per share

Finance - Biotech company reports $132M in net income

Finance - Biotech company reports income of $0.30 per share

Finance - Biotech research company announces 30% increase in third quarter revenues

Finance - Biotech stem cell-focused company raises $22.5 million in new equity financing

Finance - CORLUX maker reports increased losses in Q3

Finance - Canadian biotech reports third quarter results

Finance - Cancer research company reports improved third quarter results

Finance - Cardiac device firm reports profit of $0.02 per share

Finance - Cardiac laser technology company reports financial results

Finance - Cellular therapy company announces convertible subordinated note offering

Finance - Chemical company reports improved results for third-quarter 2004

Finance - Chronimed reports positive Q1 results; merger with MIM on track

Finance - Community Health Systems reports 18.4% increase in Q3 revenues

Finance - Company reports a 35% Cubicin revenue increase

Finance - Contract research company announces five-year record results

Finance - CorVel announces dip in earnings

Finance - Dental device firm reports loss of $0.05 per share

Finance - Dental products company reports record sales and earnings in Q3

Finance - Device company reports record $52.3M sales

Finance - Device firm reports 37% increase in sales

Finance - Device maker reports 41% revenue growth in third quarter

Finance - Diagnostics company announces third quarter financial results

Finance - Diagnostics maker reports income of $0.08 per share

Finance - Drug delivery firm reports 43% increase in revenue

Finance - Drug delivery systems manufacturer reports first quarter financial results

Finance - Drug discovery company announces third quarter 2004 financial results

Finance - Electrophysiology company reports record Q3 revenues

Finance - EnSite maker reports Q3 results quarterly revenue of $11.4 million

Finance - Epilepsy diagnostic maker reports strong cash position

Finance - Genomic-analysis company reports Q3 loss of $1.2 million

Finance - Genomics company reports increased Q3 revenues

Finance - Genomics-based pharma reports on Q3, including advances in pipeline

Finance - Gentiva reports Q3 2004 EPS of $0.17 and double-digit medicare revenue increase

Finance - German biotech expands to United States

Finance - HCA reports increased third-quarter revenues

Finance - Hand-held diagnostics company closes $29.2 million series D financing

Finance - Health Grades announces Q3 results: Third consecutive quarter of net income

Finance - Healthcare company reports 12% increase in third quarter sales

Finance - Healthcare company reports third quarter results

Finance - Healthcare investment company announces financial results

Finance - Healthcare operator begins trading on New York Stock Exchange

Finance - Henry Schein reports third quarter net sales of $1.03 billion

Finance - Horizon Health announces fourth quarter earnings increase of 14%

Finance - Human bone and bone connective tissue company reports financial results

Finance - Human therapeutics company reports third quarter financial results

Finance - Hyaluronidase maker approved for listing on American Stock Exchange

Finance - IDEXX Laboratories announces third quarter financial results

Finance - IDX Systems Corporation reports third quarter financial results

Finance - Immunodiagnostics company announces increased Q3 sales

Finance - Information Holdings reports third quarter financial results

Finance - Information technology company declares quarterly dividend

Finance - Information technology company reports first quarter results

Finance - InsWeb reports third quarter financial results

Finance - IntegraMed reports 22% increase in third quarter revenues

Finance - Lab IT company reports loss of $0.21 per share

Finance - Lifesciences company closes private placement transaction

Finance - Long-term healthcare real estate company pleased with third quarter results

Finance - Medical laser company reports third quarter results

Finance - Medical products distributor announced financial results

Finance - Medical products manufacturer announces record third quarter revenues of $11.8M

Finance - Medical technology company's revenue up 38%; EVLT product line revenue up 45%

Finance - Microarray maker announces $7.5M Series A financing

Finance - Monitor maker reports higher first-quarter results

Finance - Nanomaterial developer announces financial results

Finance - Nebulizer developer reports loss of $0.96 per share

Finance - Net Q3 income allocable to ORACEA-maker stockholders of $0.05 per share

Finance - Nutritional supplements company reports loss of $0.15 per share

Finance - Nutritional supplements firm reports third quarter revenue to exceed $10M

Finance - Operative surgical robotics developer reports record third quarter sales

Finance - Optetrak maker reports Q3 revenue up 15% to $19.5 million

Finance - Orthopedics company reports Q3 net income per diluted share of $0.11

Finance - Patent awarded for rapid acoustic transfer of nanovolumes in microplate formats

Finance - Pharma company reports second quarter financial results

Finance - Pharmaceutical company completes financing round in support of clinical development

Finance - Pharmaceutical company reports preliminary third quarter results

Finance - Pharmaceutical company reports sales of $96M in third quarter

Finance - Pharmaceutical company reports third quarter results

Finance - Pharmaceutical company reports third-quarter sales and earnings

Finance - Pharmaceutical distributor reports first-quarter loss

Finance - Pharmaceutical firm reports gross margin of 44%

Finance - Pharmaceutical firm reports second closing of $21.5M private financing

Finance - PuraMatrix maker secures $1.7M financing

Finance - Spinal device company reports third quarter results

Finance - Supplier of medical and surgical disposable products reports record revenue

Finance - Supply chain management solutions reports financial results

Finance - TF decoy technology company reports Q3 results

Finance - Touch feedback technology developer reports third quarter financial results

Finance - U.S. FDA approval of FOSRENOL triggers US$18 million payment

Finance - Venture fund invests in Othera Pharmaceuticals

Finance - Weight management products provider announces financial results

Fitness & Wellness - Olympic champ says he had collapsed lung before Athens

Flu Vaccine - Arkansas flu shots almost gone

Flu Vaccine - Coconino, Arizona, officials to administer flu shots

Flu Vaccine - Flu shot lottery winners recieve their prize

Flu Vaccine - Hawaii to hold flu shot clinics for chronically ill

Flu Vaccine - Illinois Governor pressures FDA for flu shot plan

Flu Vaccine - Local agencies in Michigan play key role in distribution of flu vaccine

Flu Vaccine - Majority of physicians say flu vaccine shortage is crisis, e-survey shows

Flu Vaccine - Minnesota nursing homes report they have enough flu vaccine

Flu Vaccine - Mississippi health officials say 50K more flu vaccines available

Flu Vaccine - Veterans Health Administration cancels flu shot clinics

Food Allergy - Sandwich ELISA for casein appears useful for identifying milk proteins in foods

Food-Borne Disease - Rapid immunoassay detects Salmonella Enteritidis in poultry

Food-Borne Illness - Nordic berries inhibit growth of harmful intestinal bacteria

Forensics - Yellow dates bruising

Forestry - Climate change and catastrophic fires linked

Formaldehyde Exposure - Formaldehyde-induced DNA adducts biomarkers of nasal cell formaldehyde exposure

Fracture Therapy - Bone graft study to be expanded based on results of severe fracture treatments

Fragile X Syndrome - Support for mental retardation needed

Free Radicals - Free radical outflow is exercise intensity dependent

Funding - Intronn Receives NHGRI grant to apply SMaRT technology to genomics

Fundraising - Lou Gehrig disease targeted by 'Curt's Pitch for ALS' program in Massachusetts

Fungicides - Systems biology company expands fungicide patent portfolio

Gastroenterology Vaccine - Regions in fimbrial adhesin FaeG suggest donor strand mechanism

Gene Analysis - Microarray-based AMASE offers a novel way to scan for gene mutations

Gene Expression - Sterically stabilized immunolipoplex enhances systemic gene delivery

Gene Mutations - Diagnostic lab offers new gene sequencing service for mutation detection

Gene Mutations - Gene mutations alter myocardial performance via changes in Ca²⁺ sensitivity

Gene Probes - Microarray analysis identifies glutathione deficiency in rodent livers

Gene Regulation - The inflammatory millieu of the pulmonary tract rules genes within its confines

Gene Research - GATA-4 transcription factor binds within regulatory regions of M₂ gene

Gene Research - Method yields endothelial RNA to facilitate studies of spatial gene regulation

Gene Research - Researchers find gene to help soybeans repel aphids

Gene Suppression - METH-2 silencing correlates with the advent of non-small cell lung cancer

Gene Transfer - Complement improves the transduction of murine liver cells

Gene Transfer - Polypeptides with select binding affinities could direct genes to neurons

Generic Drugs - Company receives approval to market generic sodium diclofenac

Generic Drugs - FDA grants final approval and first-to-file status for gabapentin tablets

Generic Drugs - Final approval granted for Citalopram HBr tablets; shipping begins immediately

Genetic Analysis - New line of genetic analyzers launched

Genetic Disorders - The Huntington disease gene IT15 is differentially expressed during development

Genetic Testing - Company expands genetic testing program

Genetic Testing - South Carolina screening newborns for more genetic disorders

Genetics & Genomics - Chromosome 7 studied for structure and function of the human genome

Genital Herpes - Viral shedding explored as a surrogate marker for genital herpes transmission

Genomics - New method for identifying alternative splicing announced

Genomics - Report describes organization of genes encoding isoforms of troponins I and T

Gestational Diabetes - Maternal serum C-reactive protein levels associated with GDM risk

Glaucoma - Istalol receives BT rating from U.S. Food and Drug Administration

Glioblastoma - 2-Methoxyestradiol inhibits proliferation of normal and neoplastic glial cells

Glycemic Control - Hypoglycemia in type 2 diabetes reviewed

Glycemic Control - Short-term chemical ablation of GIP receptor causes glucose intolerance

Granular Cell Myoblastoma - Genetic profile of granular cell tumors determined

Group B Streptococcus Infection - Real-time PCR GBS detection test rapidly screens intrapartum vaginal specimens

HIV/AIDS - Pediatric HIV/AIDS medical centers to be built in Africa

HIV/AIDS Epidemiology - Doctors Without Borders says children with HIV/AIDS dying needlessly

HIV/AIDS Drug Resistance - Incomplete HIV suppression may account for resistant mutations in brain

HIV/AIDS Education - HIV/AIDS knowledge lowest among Chinese college students from rural areas

HIV/AIDS Epidemiology - Use of blood donor data for HIV surveillance does not reflect normal population

HIV/AIDS Genetics - HIV-1 recombination is a major evolutionary force affecting genetic variation

HIV/AIDS Healthcare - Deaf gay men perceive HIV/AIDS healthcare providers as lacking in compassion

HIV/AIDS Pathogenesis - Non-syncytia-inducing HIV inhibits replication of syncytia-inducing strains

HIV/AIDS Perinatal Transmission - Nevirapine does not prevent perinatal HIV-1 transmission in the field

HIV/AIDS Prevention - Global communication effectively transfers HIV prevention strategies

HIV/AIDS Research - 2-Aminopurine fluorescence binding assay quantitates HIV-1 TAR interactions

HIV/AIDS Research - CD4 infection with infectious HIV-1 leads to IL-2 promoter hyper-responsiveness

HIV/AIDS Research - CD4+ cell loss in T-tropic HIV-1 infection is not directly mediated by apoptosis

HIV/AIDS Research - Conserved carboxy terminus of HIV-1 Gag important for virion assembly/release

HIV/AIDS Research - Cyoplasmic p53 may enhance the accuracy of HIV-1 RT DNA synthesis

HIV/AIDS Research - Determinants within gp120 and gp41 contribute to CD4 independence of SIV Env

HIV/AIDS Research - HIV-1 integration sites flanked by potential MARs can act as promoters

HIV/AIDS Research - HIV-infected CD8 lymphocytes generated through infection of activated CD8 cells

HIV/AIDS Research - Hsp70 protects cells from cell cycle arrest and apoptosis induced by HIV-1 Vpr

HIV/AIDS Research - IgMs selectively cleave HIV gp120 by a nucleophilic mechanism

HIV/AIDS Risk - Adolescent woman may be more susceptible to HIV infection than men in Cameroon

HIV/AIDS Screening - HIV screening inadequate in North Carolina jails

HIV/AIDS Testing - British embassy in Zimbabwe denies racism, staff unrest

HIV/AIDS Therapy - Antiretroviral treatment decisions based on toxicity/resistance/convenience

HIV/AIDS Therapy - Each nucleoside/nucleotide backbone of HIV therapy has its advantages

HIV/AIDS Therapy - Genotypic HIV drug resistance in plasma may predict resistance in genital tract

HIV/AIDS Therapy - HIV viral load after 4 weeks of HAART predicts virologic outcome at 24 weeks

HIV/AIDS Therapy - Improved activity of abacavir prodrug due to increased CBV-TP metabolites

HIV/AIDS Therapy - Mandela urges South Africans to participate in AIDS survey

HIV/AIDS Therapy - Marketing authorization application submitted for Tipranavir

HIV/AIDS Therapy - Mechanism elucidated for bleomycin inhibition of HIV-1

HIV/AIDS Therapy - NRTIs decrease mitrochondrial DNA synthesis and oxidative enzyme content

HIV/AIDS Therapy - Quality of life increased with enfuvirtide plus optimized background regimen

HIV/AIDS Therapy - Safety data should not be extrapolated from early to new HIV protease inhibitors

HIV/AIDS Transmssion - Woman gets jail time for violating HIV law

HIV/AIDS-Related Cardiology - Surgical drainage not justified in AIDS-related cardiac tamponade

HIV/AIDS-Related Depression - Nonadherence to HAART independently associated with depression

HIV/AIDS-Related Insulin Resistance - Indinavir increases glucose production in healthy HIV-uninfected men

HIV/AIDS-Related Mycobacterium - Mycobacterium avium complex infection in HIV infection rare in the era of HAART

HIV/AIDS-Related Nutrition - Nutrition management is complicated in HIV-infected persons

HIV/AIDS-Related Renal Disease - Increased prevalence of HIV-related end-stage renal disease is minimal

HIV/AIDS-Related Wasting Syndrome - Hyperphagia contributes to normal body composition in asymptomatic HIV infection

Haemophilus - PCR used to determine serotype of Haemophilus influenzae strains

Haemophilus Vaccine - Haemophilus influenzae type b conjugate vaccines reviewed

Haemophilus Vaccine - Intranasal vaccine reduces colonization of Haemophilus influenzae

Hand Dermititis - BAL4079 moves into phase III

Hantavirus - Hantavirus pulmonary syndrome outbreak documented in Los Santos, Panama

Head and Neck Cancer - Global gene expression profiles determined in HNSCC tumor lines

Head and Neck Cancer - Suicide gene therapy and radiation kill nasopharyngeal carcinoma xenografts

Health & Environment - Less lead in blood, breast milk attributed to education, prevention program

Health Education - Publication aims to improve women's health knowledge

Health Education - Texas Board approves health book after publishers change definition of marriage

Health Insurance - Blue Cross Blue Shield of Michigan, Blue Care Network sell new offerings

Healthcare & Politics - Senior living facilities operator praises New York's new assisted living law

Healthcare Access - Attention, commitment to healthcare needs, benefits MCOs, underserved patients

Healthcare Coverage - Alabama Legislature looks into controlling health insurance costs

Healthcare Coverage - Blue Cross lawyers make case for halt on healthcare contract

Healthcare Coverage - Board looks for more funding for breast and cervical cancer screenings

Healthcare Coverage - California officials look for fixes after healthcare measure fails

Healthcare Coverage - Companion HealthCare to cover FluMist nasal spray

Healthcare Coverage - Company expects that VentrAssist to be reimbursed during trials

Healthcare Coverage - Consulting firm, Business Coalition on Health partner to evaluate health plans

Healthcare Coverage - Douglas says he'll work with Democrats in legislature

Healthcare Coverage - Insurance products company appoints member to board of directors

Healthcare Coverage - Lack of health insurance a growing problem in most states

Healthcare Coverage - New health board approves, rejects hospital proposals

Healthcare Coverage - New nonprofit organization established to improve health care in Minnesota

Healthcare Coverage - Report says Wyoming families face big problems

Healthcare Coverage - SMC launching major initiative to fight rising healthcare insurance costs

Healthcare Coverage - Study shows 16% increase in 2003-2004 HMO Medicare enrollment in 6 states

Healthcare Coverage - Study shows healthcare workers experience higher rates of disability

Healthcare Coverage - Survey finds slowing of HMO and PPO renewal rate increases

Healthcare Coverage - United States-Mexico health week gets support from health insurance plans

Healthcare Delivery - Performance incentives improve quality of TB/HIV healthcare delivery

Healthcare Disparities - Blacks get HIV medications later than whites

Heart Disease - Prothrombin time monitor under development for use in U.S. clinical trials

Heart Disease Risk Factor - Dyslipidemia in type 2 diabetes reviewed

Heart Disease Risk Factor - Fibrinogen and fibrin clot structure in diabetes reviewed

Heart Disease Risk Factor - Hypertension and smoking decreasing among U.S. adults with diabetes

Heart Disease Risk Factor - MKP-1 expression and cGK I alpha prevent diabetes-associated abnormalities

Heart Disease Risk Factor - Non-HDL cholesterol level predicts vascular inflammation in type 2 diabetes

Heart Disease Risk Factor - Postprandial hyperglycemia increases risk of cardiovascular disease

Heart Failure - Changes in histidine-rich protein levels are linked to impaired cardiac function

Heart Failure - Corin gene is upregulated in hypertrophic cardiomyocytes and failing myocardium

Heart Failure - Degenerated cardiomyocytes showed features indicative of autophagic cell death

Heart Failure - Downregulation of corin mRNA may be a mechanism for ANP release in heart failure

Heart Failure - Even mild kidney problems raise mortality risk in women with heart failure

Heart Failure - Few studies have been conducted that assign risk to specific polymorphisms

Heart Failure - Heart failure may be accentuated by a downregulation of myocardial TNF-alpha

Heart Failure - Reduced Cx43 expression leads to slowed conduction

Heart Failure - Report reviews evidence implicating NO in the pathophysiology of heart failure

Heart Failure - Sympathetic burst power reflects both burst frequency and amplitude

Heart Surgery - CD29 mediates endothelial neutrophil migration during extracorporeal circulation

Heart Surgery - Women at greater risk of leg infection after heart surgery than men

Hematology - Mice expressing defective human factor IX aid hemophilia B research

Hemophilia - Regulatory application submitted in Japan for Advate

Hemophilia B - Factor IX replacement postpartum may prevent bleeding in women with deficiency

Hepatitis - Hepatitis study information presented at conference

Hepatitis - New data on PEG-INTRON presented at conference

Hepatitis A Virus - Ninety-two people infected with hepatitis A in central Romanian

Hepatitis B Virus - EMEA issues positive opinion on hepatitis B vaccine containing Corixa's MPL

Hepatitis B Virus - Hepatitis B cases down 89% among children, adolescents

Hepatitis C - Application submitted for approval of hepatitis C product in Europe

Hepatitis C Virus - Two hepatitis C studies with PegIntron plus Rebetol therapy initiated

Hepatocellular Carcinoma - Interleukin-12 gene transfer and electrosonporation targets liver cancer

Herpes Simplex Virus - HSV-1 VP16 recruits general transcription factors/coactivators to IE promoters

Herpesvirus - E2F1/CDK2 promoter activation requires N- and C-terminal regions of KSHV LANA

Herpesvirus - Kaposi sarcoma-associated herpesvirus immediate early gene activity explored

Heymann Nephritis - Chemically modified renal antigen produces Heymann nephritis

Hip Replacement - Harris-Galante total hip arthroplasty has excellent long-term outcome

Hip Replacement - Spacer endoprosthesis can resolve infection

Hip Replacement - Use of strut and impacted cancellous allografts reduces mechanical failure

Human Genome - ENCODE array launched to uncover function of human genome

Human Herpesvirus 6 - DC-SIGN expression altered at transcriptional level by HHV-6 infection

Human Papillomavirus - Microscopy/RT-PCR identifies mechanisms of long-term HPV oral mucosal infection

Human Papillomavirus Vaccine - ISCOMATRIX adjuvant is suitable for use in anticancer vaccines

Huntington Disease - Role of adenosine in neurodegeneration elucidated

Hyperbilirubinemia - Stanate hyperbilirubinemia treatment released from clinical hold

Hyperglycemia - Management of acute hyperglycemic crisis in elderly outlined

Hyperphosphatemia - U.S. FDA approves FOSRENOL to reduce phosphorus levels in ESRD patients

Hyperplasia - Benefits of doxazosin may be additive in benign prostatic hyperplasia

Hypertension - Bosentan improves quality of life, prognosis for PAH patients

Hypertension - Health Canada approves therapeutic breathing device to lower blood pressure

Hypertension - Progress is expected to lead to specific antihypertensive treatments

Hypertension - ROS-induced Ca²⁺ sensitization is through activation of Rho

Hypertension Risk Factor - Blood pressure response not predicted by glycemic effects of sugar drinks

Hypertension Risk Factor - Renin-angiotensin system activated in rats with obesity and hypertension

Hypertensive Heart Disease - Review describes drug treatment of hypertensive heart disease

Hypertrophic Cardiomyopathy - Multiple mechanisms are involved in pathogenesis of phenotypes in cardiomyopathy

Hypogonadism - Europe approves STRIANT for testosterone replacement in hypogonadal men

Hypotension - Arterial BP control based on neural network during acute hypotension reported

Hypothyroidism - Thyroid cancer precursor lesions studied in Hashimoto thyroiditis patients

Hypoxia - Technique provides a simple way to create hypoxic/ischemic conditions in vitro

Idiopathic Pulmonary Fibrosis - Actimmune data in idiopathic pulmonary fibrosis presented at ACCP meeting

Imaging - Imaging technology for detection of pediatric eye diseases available for adults

Imaging - Lesion evaluation tool receives FDA clearance

Imaging - MRI helps diagnose diseases of abdomen and pelvis during, after pregnancy

Imaging - Medical technology company offers update on SLICES technology

Imaging - Nonlinear parameters better than linear in finding diseased tissue

Imaging - U.S. FDA clears flexible endomicroscope

Immune Respose - Cell surface MHC class II expression inhibited by Salmonella

Immunizations - Missed opportunities for adult immunization in primary care outlined

Immunizations - Study indicates vaccine protects against cervical cancer

Immunology - Cellular immune responses can develop in humoral non-responders to HBV vaccine

Immunology - Fas ligand overexpression spawns inflammation in the central nervous system

Immunology - Fresh blood and liver natural killer cells demonstrate genetic differences

Immunology - IL-8 involved in cervical dilatation but not in prelabor cervical ripening

Immunology - Immunoassay for gp130 binding to IL-6/lL-6R complex devised

Immunology - Loss of CD154 impairs Th2 extrafollicular plasma cell response

Immunology - Nitric oxide regulates PMN-brain microvessel endothelial cell interactions

Immunology - Novel assay provides simultaneous measure of serum and PBMC cytokines

Immunology - Subnormal immunity to measles in found in HIV+ mothers and infant cord blood

Implants - Titanium, HA-coated implants studied in human bone-derived cells

Infection Control - New antibacterial agent slated for Italian launch

Infective Endocarditis - New risk factors for endocarditis have emerged

Infertility Therapy - Fewer injections needed to prevent premature ovulation

Inflammatory Bowel Disease - Prospective 20-year study finds pregnant women with IBD have healthy babies

Inflammatory Bowel Disease - Regulatory T cells may be a potential therapeutic tool for IBD

Influenza - Americans seek alternatives for flu protection

Influenza - Annual vaccination associated with decreased risk of death in elderly

Influenza - CDC chief: Flu season off to slow start

Influenza - FDA grants clearance for NOW Influenza A & B test

Influenza - Flu vaccine maker taking action to return to market as reliable supplier

Influenza - Strategies offered for flu vaccine rationing

Influenza Vaccine - Efficacy of influenza vaccination in healthy adults decreases with age

Influenza Vaccine - FluMist producer announces expanded delivery

Influenza Vaccine - Stability of influenza hemagglutinin in vaccine bulk material studied

Influenza Vaccine - Technology released for rapid production of influenza vaccines

Influenza Virus - Influenza virus infection of neonatal rat brain described

Information Technology - 3D imaging software company signs agreement to integrate CT colon CAD technology

Information Technology - Cancer institute installs research, management software system

Information Technology - Company specializing in e-script technology appoints two to board of directors

Information Technology - DRC wins $4.8M contract to support the U.S. Navy's HIV management system

Information Technology - Daou to build integrated case management system for Indian Health Service

Information Technology - DataBay Resources launches NavigateNet Beta testing

Information Technology - Diversified Security Solutions wins $800,000 contract with Huntington Hospital

Information Technology - EMSI deploys UnityOne Intrusion Prevention Systems to secure medical information

Information Technology - Erlanger selects Ibex PulseCheck to automate EDs

Information Technology - Henry Ford Health System adopts digital imaging system

Information Technology - IT company continues installation of MedLink at medical laboratories in Brazil

Information Technology - IT company to provide support system for U.K. patient records service program

Information Technology - IT company, electronic prescription data provider reach services agreement

Information Technology - Information technology companies expand strategic alliance

Information Technology - Information technology company releases new practice management system

Information Technology - Information technology company releases system for health plan administration

Information Technology - Intravenous drug compatibility database software system introduced

Information Technology - Monongahela Valley Hospital selects passive tracking software

Information Technology - Multi-disciplinary scientist-moderated online forum launched at NeuroScience '04

Information Technology - NIH grant to be used to measure surgical care processes

Information Technology - Nebraska renews, expands contract with healthcare information services company

Information Technology - Pediatrics Web site logs 530,000 unique visitors

Information Technology - PowerCenter data integration platform paired with HP Integrity servers

Information Technology - Software for life sciences study and research launched

Information Technology - Use of TrialXS extended into the Asia Pacific region.

Injury Prevention - Accident risk factors associated with sleepy truck drivers

Injury Prevention - Alliance to create injury prevention program for students

Injury Prevention - BB guns injure thousands each year

Insulin - Insulin regulates expression of protein gene enhancer via different pathways

Insulin - Insulin stimulates fatty acid transport by regulating expression of FAT/CD36

Insulin Resistance - Alpha-lipoic acid mitigates insulin resistance in Goto-Kakizaki rats

Insulin Resistance - Fad diets high in saturated fats can induce insulin resistance

Insulin Resistance - Minimal model estimation of insulin sensitivity from oral test validated

Insulin Resistance - SomatoKine receives European orphan drug designation

Insulin Secretion - Random insulin granule diffusion required for recruiting granules for release

Insulin Therapy - Cleo 90 infusion set gains FDA clearance

Irradiation - Whole body irradiation damages fibroblasts in wounds

Irritable Bowel Syndrome - Studies find sex-based differences in gastrointestinal pain

Ischemia - Estrogen receptor is involved in neuroprotection in an ischemia model

Ischemia - F₁ F₀ -ATPase contributes to decline in energy reserve during ischemia

JC Virus - PMA and IL-1beta dramatically increase JC virus transcription in glial cells

Japanese Encephalitis - Sera against ChimeriVax-JE vaccine protects against encephalitis virus

Kaposi Sarcoma Herpesvirus - KSHV ORF36 protein kinase activates c-Jun N-terminal kinase signaling pathway

Kaposi Sarcoma-Related Herpesvirus - Poly(ADP-ribose) polymerase 1 binds to KSHV TR and modulates latency replication

Kidney Disease - Dialysis patients half as likely to be treated after a heart attack

Kidney Disease - Do statins reduce dialysis patients' risk of heart disease?

Kidney Disease - First human trial of bioartificial kidney shows promise for acute renal failure

Kidney Disease - Is the long wait for kidney transplants worth it?

Kidney Transplantation - Body mass index influences graft function in renal transplant patients

Knee Replacement - "Wandering resident" revision arthroplasty technique evaluated

Knee Replacement - Total articulating cementless knee shows promise

LDL Apheresis - Iron metabolism is modified by regular LDL apheresis treatment

Lab Equipment - Stem cell monitoring system available to labs on flow cytometry system

Legal Issues - Nasal spray users suing over alleged loss of smell

Legal Issues - New Mexico State board revokes pharmacist's license

Legal Issues - State pulls license of pharmacy on narcotics charge

Legal Issues - Suicide victim family seeks damages from mental health facility

Legal Issues - United Healthcare companies to pay $2.2 million to North Carolina

Legal Issues - Washington man sentenced for stealing cancer patient's identity

Leishmania - Leishmania donovani activates NF-kappaB in macrophages through ROS intermediates

Leishmaniasis - Encapsulated amphotericin B effective, economical against leishmaniasis

Leprosy Therapy - Immunotherapy increases effectiveness of treatment for leprosy

Leptin Studies - Leptin and insulin downregulate angiopoietin-like protein 3

Letter to the Editor - Study links low HDL levels with increased risk of postmenopausal breast cancer

Leukemia - Antiviral therapy for adult T cell leukemia lymphoma is promising

Leukemia - Nippon Shinyaku Co., Ltd. receives approval to market TRISENOX in Japan

Leukemia - Obesity increases older women's risk of acute myelogenous leukemia

Leukemia - Orphan drug designation granted for the treatment of leukemia

Leukemia - Signaling mechanisms underlie human leukemia cell life/death switching

Leukemia - U.S. FDA grants orphan drug designation to acute myelogenous leukemia drug

Leukemia Therapy - Guidelines to define therapeutic strategies for leukemia described

Licensing Agreement - Company gets exclusive worldwide license for cholesterol-reducing nutraceutical

Lipid Metabolism - Use of SNPs doubles estimates of genetic variance of HDL and APOE AI in women

Lipid Studies - Atorvastatin causes a greater reduction in LDL-cholesterol than pravastatin

Lipid Studies - Dietary copper, zinc supplements effect on atherosclerosis studied

Lipid Studies - Red wines contain antioxidants that provide protection against LDL oxidation

Lipolysis - Carboxylesterase 3 is major adipocyte lipase

Liver Cancer - Hepatitis B virus infection agitates enzymes involved in liver cancer invasion

Liver Cancer - RFA safe for treating liver tumors pushing on GI tract

Liver Transplantation - Hepatic Na⁺, K⁺-ATPase reduced after ischemia-reperfusion

Liver Transplantation - MELD score changes before liver transplantation do not predict mortality

Lung Cancer - Biotechnology company receives grant to create lung cancer therapies

Lung Cancer - Company develops early diagnostic test for lung cancer

Lung Cancer - EGF receptor gene mutations are common in lung cancers from non-smokers

Lung Cancer - cis-Pt(II) complex of 3-aminoflavone induces lung tumor apoptosis and necrosis

Lymphoma - Childhood allergies appear to increase risk of blood cancers

Lysosomal Storage Disease - Modified bone marrow cells improve cognition in mucopolysaccharidosis models

Macular Degeneration - Eye health company presented age-related macular degeneration trial results

Macular Degeneration - Nutraceutical firm launches Oculair for eye, body health

Malaria - Malaria protein that binds to placental cells may serve as vaccine target

Malaria - Platelet count is an important clue to the diagnosis of malaria

Malaria - Submicroscopic P. falciparum infection may affect immunity during pregnancy

Malaria - Weather monitoring warns of malaria epidemics in African highlands

Malaria Genomics and Genetics - Genetic diversity of malaria merozoite protein gene determined

Malaria Vaccine - Malaria vaccine based on Plasmodium Duffy binding protein evaluated

Malpractice Insurance - Oregon Measure 35, malpractice cap, may be revisited by legislature

Malpractice Insurance - Survey shows doctors considering closing their practices

Malpractice Insurance - Wyoming looks ahead after voters reject malpractice damage limits

Managed Care - Mental health service provider announces withdrawal from Texas NorthSTAR network

Market Analysis - Growing patient volumes encourages adoption of RFID

Market Analysis - Pharma firms devote half of research to strategic opportunities

Market Analysis - Report indicates disease management firms show prognosis for growth

Marketing Agreement - Companies renew Canadian Pennsaid agreement

Measles Vaccine - Economic analysis of mass measles vaccination in South Africa reported

Measles Vaccine - Measles-specific CD4 T cell memory decreases in vaccinated subjects

Measles Vaccine - Patients should receive measles vaccine after stem cell transplantation

Medical Devices - Biotech company submits FDA application to market blood component separator

Medical Devices - Eye photo taken through microscope wins Olympus scientific imaging competition

Medical Devices - First left ventricular assist implant at Seattle center under Reliant completed

Medical Devices - Holographic assay measures anisotropic energy transport in flowing polymers

Medical Devices - LaryngoSeal Laryngeal Mask from Nellcor previewed at conference

Medical Devices - Medical device company expands product line

Medical Devices - Medical device company introduces new spinal technologies

Medical Devices - NYU Cancer Center features new hyperthermia system

Medical Devices - New chairman of Washington biomedical association calls for plan

Medical Devices - Optical technology company introduces UIS2 Microscope Optical System

Medical Devices - Radiofrequency generator for vein reflux, varicose veins treatment introduced

Medical Devices - Study finds Vasotrac is less intrusive than conventional blood pressure monitors

Medical Devices - Survey expects laboratory product purchases to increase in 2005

Medical Devices - Vascular disease company concludes enrollment of HEALING II clinical trial

Medical Education - Teens fresh out of high school head to medical school

Medical Errors - Apology policies for medical mistakes gaining attention

Medical Errors - Doctors may be subject to background checks

Medical Errors - Limiting interns' work hours can substantially reduce serious medical errors

Medical Errors - New York puts doctor on probation for inmate's death

Medical Malpractice - New report lauded as evidence that medical malpractice reform works

Medical Marijuana - Nearly three-fourths of Western States have medical marijuana laws

Medical Training - New curriculum seeks to standardize training of cancer physicians worldwide

Medicare - Coverage expansion proposed for cancer patients

Medicare - Payment rates and policy changes announced for hospital outpatient services

Melanoma - M-Vax registered for commercial marketing, distribution in France

Meningococcal Vaccine - Neisseria meningitidis vaccine safe and immunogenic in infants

Meningococcal Vaccine - Peptide mimotopes of N. meningitidis polysaccharide described

Meningococcal Vaccine - Putative vaccine antigens from Neisseria meningitidis identified

Menopause Therapy - New Bio-E-Gel phase II efficacy results presented at ASRM meeting

Mental Health - Michigan citizen's group lauds governor's mental health commission report

Mental Health - U.S. Psychiatric & Mental Health Congress highlights advances in mental health

Mental Health - X-box binding protein 1 C--116G polymorphism is not linked to bipolar disorder

Mental Heath - Family therapy reduces stress symptoms in adolescent survivors of cancer

Mergers & Acquisitions - Biopharmaceutical company acquires minority interest in TKT Europe-5S AB

Mergers & Acquisitions - Company signs letter of intent to acquire IGI; holding company to be formed

Mergers & Acquisitions - Filtration, separations and purification company acquire chromatography business

Mergers & Acquisitions - Hospital management company completes buyout of Houston-based Triumph HealthCare

Mergers & Acquisitions - Long-term care operator shareholders consider merger with National Senior Care

Mergers & Acquisitions - Medical staffing company signs intent letter to purchase assets of staffing firm

Mergers & Acquisitions - Newborn and maternal services provider acquires Atlanta neonatal physician group

Mergers & Acquisitions - Nutritional supplement business to acquire Pilgrim's Natureway business

Mergers & Acquisitions - Pharmaceutical firm acquires manufacturer of spinal implant devices

Mergers & Acquisitions - Rehab-focused company announces acquisition of three seating device companies

Mergers & Acquisitions - Venture capital firm announces acquisition of Spine Next by Abbott Laboratories

Mesangial Cells - Abnormal light chains induce divergent phenotypic transformations

Minibodies - Antibody research to be published in hematology journal

Mitochondria - Mitochondria depend upon ATP synthase to make supramolecular structures

Mitochondria - Model explains major features of physiological mitochondrial Ca²⁺ transport

Mitral Valve Disease - Genetic link suggested in deaths from cardiac valve diseases

Molecular Biology - HNA gapmer oligonucleotides supply potent antisense activity

Molecular Diagnostics - DNA-focused company, Siemens form joint working group on molecular diagnostics

Molecular Imaging - PET reporters monitor activity following gene transfer

Monitoring - ODOC contracts for remote ECG screening

Monoclonal Antibodies - Immunoassay groups MAbs by topographical epitopes

Mother-to-Child HIV Transmission - P-glycoprotein inhibitors plus indinavir might reduce vertical infection

Motor Neurons - Embryonic SC-derived motoneurons develop appropriate transmitter receptors

Multiple Sclerosis - Lead investigator named for multiple sclerosis trial

Multiple Sclerosis - MS management during pregnancy has special considerations

Multiple Sclerosis - Pharma company presents multiple sclerosis data at conference

Multiple Sclerosis - Pharmaceutical companies partner to develop oral treatment for MS

Murine Leukemia Virus - Real-time PCR evaluates X-MuLV removal during protein purification

Muscular Dystrophy - Calsequestrin expression reduced in dystrophic murine skeletal muscle

Muscular Dystrophy - Dystrophin gene therapy overcomes immune system hurdles in murine models

Mutagenesis - Adenomatous polyposis coli gene isoforms curtail cancer cell growth

Myocardial Infarction - Beneficial effects of ACE inhibitors is due to renin-angiotensin blockade

Myocardial Infarction - Bone marrow cells can acquire cardiac phenotype in vivo

Myocardial Infarction - Heart cell therapy revitalizes the ailing heart

Myocardial Infarction - Interruption of the Fas/Fas ligand system may treat heart failure

Myocardial Infarction - Noninvasive wearable heart care offers continuous monitoring

Myocardial Infarction - Positive results from clinical trial of arterial inflammation drug

Myocardial Infarction - U.K.'s first heart pump inserted without surgery provides "rest" after heart op

Myocardial Oxidative Stress - Selenium supplement improves myocardial stress, prevents cardiac dysfunction

Myocardial Relaxation - Myocardial relaxation is characterized by a 3-dimensional unfolding deformation

Nanotechnology - Nanotechnology-based products starting to have big consumer impact

Natural Products - HIV-1 inhibitory compounds isolated from Calophyllum brasiliense leaves

Neonatal Sepsis - High-risk-based antibiotic prophylaxis better prevents onset of GBS sepsis

Neovascularization - Bone marrow-derived cells do not contribute to tumor endothelialization

Neural Stem Cell Research - Beta₁ integrins mediate stratum-derived neural SC adhesion and migration

Neuroblastoma Therapy - Microtubule alterations identified in drug-resistant tumor cells

Neurodegeneration - The Mre11 DNA repair complex is reduced in Alzheimer disease brains

Neurodegenerative Diseases - Three new drugs could shake off the (brain) rust

Neuroendocrinology - Personality, HPA axis reactivity differ between hirsute and nonhirsute women

Neurology - Awareness campaign launched after several drug prescribing errors

Neurology - New mouse model for spinal muscular atrophy

Neuropathic Pain - Pharmaceutical firm earns milestone on advancement of pain drug

Neuroprotection - L-carnitine exhibits neuroprotective effect in rats

Neuroscience - Antiangiogenic protein fragments harbor amyloid characteristics

Neuroscience - Antipsychotic-induced changes in global pallidus dopamine levels characterized

Neuroscience - Coupled oscillators control morning and evening Drosophila locomotion

Neuroscience - Facial nucleus may play role in regulation of rat respiration

Neuroscience - Spontaneous firing in dorsomedial SCN neurons characterized

Neurosurgery - MAYFIELD Infinity Support System to launch in the United States

Neurosurgery - Vascular complications of endoscopic transsphenoidal surgery characterized

Neurotoxicity - Ketamine promotes neuronal apoptosis

Neurotoxicity - Methylmercury induces free radicals in cerebral cortical astrocytes

Neurotransmission - Dopamine blocks the effects of vascular growth factors on endothelial cells

Nicotine Addiction - Cigarette smoking a serious public health threat in China

Nicotine Addiction - Long-term medication and counseling help smokers quit successfully

Nicotine Addiction - Nicotine's addictive hold increases when combined with other chemicals

Nicotine Addiction - Receptor subunit could be prime culprit for addiction response to nicotine

Nicotine Addiction - Smoking triggers early onset of pancreatic cancer

Nicotine Vaccine - Riboflavin used for antibody-catalyzed oxidation of nicotine

Non-Hodgkin Lymphoma - Antibodies with activity against non-Hodgkin lymphomas characterized

Non-Hodgkin Lymphoma - BEAM with only cytokine support effective in high-risk patients

Norovirus - Colorado students, staff being warned of norovirus outbreak

Norovirus - Number sickened by norovirus at Las Vegas Strip hotel tops 1,200

Nosocomial Infection - S. epidermidis colonization of indwelling medical devices studied

Nosocomial Infection - Distribution of C. difficile toxinotypes characterized

Nosocomial Infection - MRSA outbreaks in NICU linked to breast milk

Nutrition - Eating fruits, vegetables reduces cardiovascular disease, but not cancer

Nutrition - FDA: Olive oil may boost heart health

Nutrition - Fast food joints more common in poor, black neighborhoods

Nutrition - Most pregnant women concerned about weight gain during pregnancy

Nutrition - Novel health food composition proves highly effective

Nutrition - Omega-3 fatty acids: good for the heart, and (maybe) good for the brain

Nutrition - Researchers advocate role of diet-gene interaction in public health nutrition

Nutrition - Study links eating fruit and vegetables with heart health

Nutrition - U.S. FDA allows use of chlorine dioxide antimicrobial for fruits, vegetables

Obesity - Health club group to provide metabolic assessment program for weight control

Obesity - U.S. CDC says obesity weighing down planes

Obesity Epidemiology - Global epidemic putting brakes on economic development

Obesity Genomics and Genetics - Genetic aspects of obesity reviewed

Obesity Genomics and Genetics - Interactions among genes, environment, and control of food intake explored

Obesity Pathogenesis - Development and function of adipose tissue reviewed

Obesity Pathogenesis - Ghrelin and Agouti-related protein increases food intake

Obesity Pathogenesis - Population increases in obesity appear to be partly due to genetics

Obesity Pathogenesis - Resistance to obesity in A/J mice not linked to hypothalamic neuropeptides

Obesity Surgery - Laparoscopic gastric bypass effectively improves obesity-related health problems

Obesity Surgery - Surgical weight loss significantly improves diabetic status

Obesity Survival and Mortality - Pitfalls of nutritional screening in injured obese patients outlined

Obesity Therapy - Belief that dieting makes a person fat questioned

Obesity Therapy - Desirability of dieting depends on likely consequences

Obesity Therapy - Lysophosphatidic acid is bioactive phospholipid

Obesity and Diabetes - Three-day low-fat diet does not improve glycemic control in type 2 diabetes

Obstetrics - Fetal alcohol syndrome prevention efforts working in Washington state

Obstetrics - Michigan women gain improved access to midwifery services

Obstetrics - Prenatal cadmium exposure has deleterious effects, rat study shows

Obstetrics - Recent pharmacological advances in treatment of preterm delivery highlighted

Obstetrics - Study absolves four genes in recurrent pregnancy loss risk in Japanese women

Occupational Health - Asymptomatic polyvinyl chloride workers show signs of liver fibrosis

Occupational Safety - Firefighters are at high risk for hospitalization

Ocular Inflammation - Positive results reported from Xibrom study in ocular inflammation

Oncogenesis - Adenoma to carcinoma hTR expression not linked to promoter methylation

Oncogenesis - Chromosome 12 encodes for genes that suppress pancreatic cancer growth

Oncogenesis - Hepatitis B X protein blocks transcription-coupled nucleotide excision repair

Oncogenesis - Members of the RB/E2F family of proteins cause aberrant survivin expression

Oncology - Bcl-xL gene overexpression boosts breast cancer lymph node metastasis

Oncology - Chromosome 9p21 shows a correlation with stage 4 neuroblastoma prognosis

Oncology - Clinical trials announced for inhaled cancer pain medication

Oncology - Cyclooxygenase-2 expression aligns with transitional cell carcinoma invasion

Oncology - Disulfiram combats melanoma metastasis

Oncology - Genetic counselors and advocacy group develop genetic discrimination brochure

Oncology - KL-6 is a serological marker for liver cancer in patients with hepatitis C

Oncology - Lab service firm reports modest increase in revenues

Oncology - Tumors exposed to chronic hypoxia show changes in microvascular function

Oncolysis - Antisense targeting of anti-apoptosis proteins radiosensitizes lung cancer

Ophthalmic Surgery - Frequency-doubled Nd:YAG laser useful for treatment of overhanging blebs

Ophthalmology - "Weekend" use matches daily drops for "lazy eye"

Ophthalmology - Bone marrow-derived stem cells save eyes from retinal degeneration

Ophthalmology - Ruboxistaurin may have a beneficial effect on diabetes-induced eye disease

Ophthalmology - Smad7 gene transfer retains epithelial integrity in injured murine eyes

Organ Donation - Marrow donor program celebrates 20,000 transplants facilitated

Orthopedic Surgery - New bone matrix product available

Osteoblasts - Extracellular mineral surfaces play role in gene expression regulation

Osteogenesis Imperfecta - RNA interference targets COL1A1 expression in mesenchymal progenitor cells

Osteopenia - Lumbar intervertebral disc degeneration shown to occur in ovariectomized rats

Osteoporosis - Calcium plus vitamin D-3 improves healing of proximal humerus fracture

Osteoporosis - Doxycycline reverses effects of ovariectomy-induced osteopenia in rats

Osteoporosis - Serum ALP, urinary NTX predict 1-year lumbar BMD response to alendronate

Osteoporosis - Surgeon general warns Americans of 'osteoporosis crisis,' recommends prevention

Outcomes - Lower level of education can impede recovery in elderly after hospitalization

Outcomes - Study compares two instruments for measuring costs and quality

Ovarian Autotransplantation - Doctors transplant ovary to woman's arm to preserve her fertility

Ovarian Cancer - Inhibitory protein involved in cancer cell apoptosis and cisplatin sensitivity

Ovarian Cancer - Second-line therapy of advanced disease with GnRH analogs shows promise

Overactive Bladder - Pharma company receives European marketing authorization for Emselex

Pain Management - Biopharmaceutical company presents information on chronic opiod use

Pain Management - Hythiam to provide HANDS protocols to Pain Management Associates

Pain Management - Ralfinamide phase II trial results for neuropathic pain released

Pain Medicine - DepoDur identified as option for postoperative pain relief

Pain Medicine - Models of sex differences in opioid analgesia inconsistent

Pain Medicine - NMDA receptors in anterior cingulate cortex mediate pain-induced aversion

Pain Medicine - Phase I trial initiated for transdermal sufentanil patch

Pain Medicine - Report: Ruboxistaurin poised to transform the diabetic neuropathy drug market

Pain Medicine - Sensitivity to pain varies by menstrual phase

Pain Medicine - Spinal PAR stimulation induces thermal hyperalgesia

Parkinson Disease - ACE inhibitor perindopril protects against MPTP-induced neurodegeneration

Parkinson Disease - Agilect improves Parkinson symptoms without worsening other adverse effects

Parkinson Disease - Drug has neuroprotective effect in preclinical model of Parkinson disease

Parkinson Disease - Foundation earmarks $3 million to validate Parkinson hypotheses

Parkinson Disease - Non-human primate model of PD may facilitate study

Parkinson Disease - Pharma companies launch Parkinson disease study with Stalevo

Parkinson Disease - Study shows reduction of alpha-synuclein expression by RNA interference

Patents - After settlement, company licenses homocysteine assay to Bayer

Patents - CTT demands arbitration regarding sexual dysfunction therapy

Patents - Drug-delivery patent granted in Australia

Patents - European patent office grants broad claims on the human hematopoietic stem cell

Patents - Pharmaceutical company consolidates patent infringement suits

Patents - U.S. Patent Office allows patent on new laser angioplasty device

Patents - U.S. patent granted for care management system

Patient Safety - Health consortium launches new patient safety tool

Patient Safety - Seven steps are key to safety in prescription drug use

Pediatric Cancer - Nongenetic causes are most likely risk factors for childhood cancer development

Pediatric Depression - Increased calls to guidance counselors by parents regarding child depression

Pediatric Hepatitis - Hepatitis B virus type D is implicated in a case of Gianotti-Crosti syndrome

Pediatric Leukemia - Donor characteristics/herpesvirus exposure impact survival in pediatric leukemia

Pediatric Obesity - Eating right a weighty subject for many New Jersey students

Pediatrics - Immigrant mothers and their children benefit from child development education

Pediatrics - Specialists' call on European Union to improve childhood cancer treatment

Percutaneous Coronary Intervention - Integrin beta3 regions that control binding of murine mAb 7E3 identified

Pericardial Constraint - Systolic nonuniformity of pericardial constraint may affect ventricular filling

Perimenopause - Health education intervention helps mid-life women in northern Taiwan

Perinatology - Recycling nutrients helps babies survive birth

Personnel - American Red Cross, Greater Cleveland Chapter names chairman

Personnel - American Specialty Health officer elected to URAC board of directors

Personnel - Amerigroup appoints new CFO

Personnel - BioSciences company adds to scientific advisory board

Personnel - Biopharma company names senior vice president of sales and marketing

Personnel - Biopharmaceutial company appoints new senior VP, chief financial officer

Personnel - Biopharmaceutical company announces new member of board of directors

Personnel - Biopharmaceutical company appoints executives

Personnel - Biopharmaceutical company appoints member to board, VP medial affairs

Personnel - Biotech company shareholders elect Carleton Holstrom to board at annual meeting

Personnel - Biotechnology company announces CEO appointment

Personnel - Bluestar Health names James D. Weiss to lead preventative care program

Personnel - Charles Theuer, MD, PhD, named VP of clinical research, CMO of biotech company

Personnel - Cockrell and Johnson appointed to senior positions at cell-therapy company

Personnel - Connecture, Inc., names Daniel Maynard new CEO

Personnel - Coventry Health Care announces organizational changes

Personnel - David Wood named VP, GM of medical device company's drug delivery business unit

Personnel - Delta Dental of California names Marland Taylor VP of systems development

Personnel - Diagnostics company announces management promotions

Personnel - Dr. Wolfgang Mutter named CEO of phage ligand company

Personnel - Drug development company board elects Hans C. Noetzli as new director

Personnel - Elliott Sigal named acting president of research institute

Personnel - End-of-life care provider announces executive promotions, organizational changes

Personnel - GTESS appoints Dan Contilli and Jim Gallagher regional sales directors

Personnel - Guenter Schirmer, MD, named medical director by drug developer

Personnel - Healthcare accrediting company elects Fazen and Metz to board of directors

Personnel - Healthcare system names new head of dental and vision services

Personnel - Information technology adds a director and officers

Personnel - Information technology company names member to board of directors

Personnel - John E. Ezcurra named director of manufacturing by oncology-focused company

Personnel - Medical device company appoints Ross Harricks new director

Personnel - Medical device company selects Virchow Krause & Company as independent auditors

Personnel - Michael B. Wood named to board of directors of healthcare industry provider

Personnel - Migraine-therapy maker names Nicholas Bluhm as CFO

Personnel - Pain-medicine company names David M. Chapman to board of directors

Personnel - Peter Biere named chief financial officer at nanotechnology firm

Personnel - Pharma company names member to board of directors

Personnel - Pharma company names president and chief executive officer

Personnel - Pharma company names president of global manufacturing

Personnel - Pharma company names senior VP business development and licensing

Personnel - Reconstructive surgery and dermatology company names board members

Personnel - Richard Riegel named VP of sales by life sciences consultancy company

Personnel - Software provider announces new board member

Personnel - Specialty pharmaceutical company creates new positions in senior management

Personnel - Timothy Adams named CFO of woman's health-focused device company

Personnel - Wade Sexton, MD, joins Genitourinary Oncology Program at Moffitt cancer center

Personnel - Yves Rosconie named president, CEO of Canadian endocrin-focused biopharm company

Pertussis Vaccine - Pertussis vaccines provide mucosal immunization of murine neonates

Pharmaceuticals - Genomics company reports breakeven net income

Pharmaceuticals - Orajel maker reports increased third-quarter results

Photoaging - Solar UV irradiation reduces collagen by blocking TGF-betaRII/Smad signaling

Physiology - Heart rates indicate a positive effect of cognitive challenges

Placental Barrier - Polychlorinated biphenyl pollutants cross the placental barrier

Plague Vaccine - Genome content of live plague vaccines defined using DNA microarray

Pneumocystis Carinii Pneumonia - Enrollment completed for DB289 clinical trial in Pneumocystis carinii pneumonia

Pneumonia - Streptococcus, Haemophilus, and Moraxella characterized

Pneumonia - Study shows Avelox IV is successful in treating pneumonia in elderly patients

Pneumonia - U.S. FDA grants fast track designation for Doripenem

Podiatry - Podiatric medical group launches 'Knock Your Socks Off' to urge foot screenings

Poliovirus Vaccine - Multiplex PCR method for identifying vaccine polioviruses developed

Poliovirus Vaccine - No link found between intussusception and oral poliovirus vaccination

Politics - National survey shows few physicians elected to Congress

Polyomavirus - Polyomavirus infection in pediatric renal transplants monitored via PCR

Preeclampsia - Animal model has features of gestational hypertension

Preeclampsia - Common thrombophilia gene variants not risk factors for preeclampsia

Prenatal Nicotine Exposure - Alterations in receptors could be responsible for bradycardia in SIDS victims

Product Licensing - Canadian health officials say too early to issue warning on Pfizer's Celebrex

Product Licensing - Mexico finds no evidence baby formula was approved for consumption

Product Licensing - Nonexclusive HCV license granted to Roche

Product Licensing - Pharmaceutical gets Israeli approval for radiological liver cancer treatment

Prophylactic Adhesion Prevention - DuraGen Plus Adhesion Barrier Matrix issued CE Mark certification

Prostate Cancer - Blocking gene opens avenues for treating prostate cancer

Prostate Cancer - CB7630 phase I data presented at Prostate Cancer Foundation scientific retreat

Prostate Cancer - CYP1B1 and PR polymorphisms may be associated with prostate cancer risk

Prostate Cancer - Foundation announces Coffey award recipients for commitment to prostate cancer

Prostate Cancer - Luteinizing-hormone-releasing-hormone causes prostatic atrophy

Prostate Cancer - Postoperative radiotherapy improves progression-free survival

Prostate Cancer - Vitamin D₃ -modulated genes identified in prostate tumor cells

Protein Signaling - Notch4 requires ankyrin repeats to staunch endothelial sprouting

Proteomics - A bidirectional on/off switch controls protein trafficking in the nucleus

Proteomics - Database of therapeutically relevant multiple pathways developed

Proteomics - Expression, function of drug transport proteins studied in rat liver model

Proteomics - Rad9 acts as a transcriptional activator of gene expression

Proteomics - The membrane anchor domain of hepatitis C virus NS5A has unique functions

Psoriasis - Safety and efficacy of efalizumab treatment reviewed

Psychology - Job-stressed women in U.S. more vulnerable than men to 9/11 trauma

Psychotropic Therapy - CLOCK gene variations may influence clozapine-induced diurnal sleepiness

Public Health - Illness from swimming in contaminated water is emerging health concern

Public Health - Overcrowded and noisy living conditions may contribute to bad health

Pulmonary - CryoCath provides AF program update

Pulmonary Fibrosis - Anticancer drug to fight fatal lung disease

Pulmonary Hypertension - Serotonin causes nuclear translocation of ERK1/ERK2 in cell mitogenesis

Pulse Oximeter - Pulse oximeter probes are safe up to 43 degrees C for 8 hours

Pythiosis Therapy - Pythium insidiosum antigens effective against vascular pythiosis

Quality of Life - Physically active HIV-infected persons have higher life satisfaction

Rabies - Health officials seek teens seen playing with rabid bat

Radiation Therapy - Troxerutin can protect non-malignant tissue from radiation damage

Radiotherapy - GENEPI could be tool to refine and fine-tune treatment for cancer

Radiotherapy - Increased investment in radiology will improve cure rates for cancer patients

Rankings - IntelliCare ranks Number 283 on 2004 Deloitte Technology Fast 500

Rankings - Medical device company ranks 11th on business journal's Growth 50 list

Regulatory Issues - "Supplements" for sexual enhancement contain prescription drug ingredient

Renal Cell Carcinoma - Patient enrollment commences for IMOxine phase II trial in renal cell carcinoma

Renal Cell Carcinoma - U.S. FDA grants orphan drug designation to BAY 43-9006

Renal Disease - U.S. FDA approves phosphate binder for patients with end-stage renal disease

Renal Failure - Reduced dilation in the brachial artery is related to renal failure severity

Renal Failure - Review evaluates evidence linking iron therapy with complications

Reperfusion - Delta-opioid receptor may play a role in ischemic preconditioning

Reproductive Biology - Iron transport protein activity increases in normal third trimester placenta

Reproductive Biology - Stat5 has distinct functions in cell proliferation, survival, differentiation

Reproductive Endocrinology - HCG gene variant seen in U.S. not found in five European populations

Reproductive Endocrinology - Oxidized LDL modulation of human trophoblast invasion studied

Reproductive Endocrinology - Pregnancy-induced growth inhibitory gene further characterized in rat model

Reproductive Health - Data show abstinence sex education reduces the initiation of sex among teens

Reproductive Medicine - Acridine orange suitable as predictor of DNA damage in sperm

Reproductive Medicine - Antioxidant vitamins can reverse DEHP-induced murine sperm disruption

Reproductive Medicine - BOULE coding sequence mutations do not account for lacking sperm production

Reproductive Medicine - NM-IF extracted human sperm cells characterized

Respiration - Study compares predictive spirometric values to those of other studies

Respiratory Distress Syndrome - EMEA validates MAA to market Surfaxin in Europe

Restenosis - Calcitonin gene-related peptide gene transfer curtails neointimal hyperplasia

Rheumatoid Arthritis - Breastfeeding may reduce and irregular menstrual cycles may increase RA risk

Rheumatoid Arthritis - Promising phase III data presented for Humira

Rotavirus - Rotavirus serotype G9P[8] responsible for outbreak in Northern Australia

Salmonella - Ingested Salmonella dose correlates with disease rate

Salmonella Vaccine - Salmonella flagellin induces systemic and mucosal immune responses

Sarcoma - Brachytherapy holds promise as treatment for once-debilitating cancers

Schizophrenia - New data show metabolic and protein processing deficits may cause schizophrenia

Schizophrenia - Psychiatric researchers find two schizophrenia genes in New Yorkers

Sepsis - Active hemoglobin enhances LPS-induced injury to endothelial cells

Sepsis - Sepsis in silico trial results published in Critical Care Medicine

Serotonin - Pharmacology of serotonin reviewed

Sexual & Reproductive Health - Rare sexually transmitted disease on rise in Netherlands

Sexual Dysfunction - Study finds high prevalence of sexual dysfunction in HIV+ women

Sexual and Reproductive Health - Growth factors confer immortality to sperm-generating stem cells

Sexually Transmitted Diseases - Vaginal swabs tested in commercial assay screen for chlamydia, gonorrhea

Shigellosis - Shigella-associated diarrhea common in rural Egyptian children

Skeletal Myoblast Transplantation - Skeletal myoblast grafts generated heterogeneity of Ca²⁺_i ) signaling

Skin Cancer - New study examines skin protection in children

Skin Cancer - Researchers discover potential skin cancer prevention target

Sleep Disorders - Sleep disorders may indicate multiple health problems, OSA study shows

Small Cell Lung Cancer - Cancer therapeutics development company files IND for small cell lung cancer

Smallpox - Potential return of smallpox, world's readiness discussed in journal article

Smallpox - Significant progress reported on smallpox vaccine

Smoking - Nevada petition would restrict smoking in public

Smoking Cessation - Funding granted to study doctors' smoking cessation practices

Spermatogonial Stem Cells - Researchers grow sperm stem cells in laboratory cultures

Spinal Cord Injury - Gene expression profile determined in contused rat spinal cord

Spinal Cord Injury - Wound healing response characterized in rats

Spinal Fusion - U.S. FDA approves artificial disc for treatment of low back pain

Spine Surgery - Surgical tools manufacturer launches SpineJet XL for spine procedures

Sports Medicine - Team-centered program helps reduce disordered eating among teen female athletes

Staffing Issues - Nursing shortage halts surgeries at major Vancouver hospital

State Medicaid - Doctor On Call pilot program reduces emergency room visits by 24%

Statin Therapy - Atorvastatin does not compromise prostacyclin receptor signaling and function

Statin Therapy - Elderly individuals are not receiving adequate lipid-lowering therapy

Stem Cell Research - California stem cell vote means competition for University of Minnesota

Stem Cell Research - California voters approve spending on stem cell research

Stem Cell Research - Companies ink agreement for new ES cell tissue-culture media

Stem Cell Research - Human ESC lines for federally funded research characterized in journal

Stem Cell Research - Hypoxia triggers stem cell proliferation followed by neuronal SC differentiation

Stem Cell Research - Molecular phenotype of renal progenitor cells identified

Stem Cell Research - Nuclear reprogramming is a key to stem cell function in regenerative medicine

Stem Cell Research - Self-renewal and multipotency demonstrated in stem cells

Stem Cell Research - Telomerase maintained in self-renewing tissues during serial regeneration

Stem Cell Transplant-Related Aspergillosis - Aspergillosis occurs later after reduced intensity versus regular SCT

Stem Cell Transplantation - Daily IV busulfan + cyclophosphamide for 4 days followed by SCT may be toxic

Stem Cell Transplantation - Multiagent strategy lowers regimen-related toxicity in children undergoing HSCT

Stem Cells - Cancer center doctor receives $25,000 award for research

Stomach Cancer - Hot-water extracts from adzuki beans reported to suppress tumorigenesis

Streptococcal Vaccine - Streptococcus pneumoniae serotype distribution in Hong Kong determined

Streptococcus Epidemiology - Invasive Streptococcus pneumoniae serotypes are least commonly isolated

Stroke - Endogenous FGF-2 ameliorates ischemic brain damage in rats

Stroke - Licensing agreement announced for citicoline therapy for stroke

Stroke - MRI-detectable microbleeds linked to cognitive impairment

Substance Abuse - Pediatricians often underestimate drug problems in adolescents

Sudden Infant Death Syndrome - Animal models help identify mechanisms related to sudden unexplained death

Surgery - Surgical repair patch receives 510(k) approval

Synthetic Blood - Synthetic red blood cell being tested at three medical schools in U.S. and Canada

Systemic Lupus Erythematosus - Biomarkers could lead to quicker and better diagnosis

Systemic Lupus Erythematosus - Newly identified biomarkers could lead to quicker, better diagnosis of lupus

Telemedicine - Ford Hospital telecasts surgery to India

Telemedicine - Remote medicine puts healthcare within patients' reach

Tetanus Vaccine - HIV lowers antibodies elicited by tetanus and diphtheria vaccination

Thoracic Trauma - Diagnostic utility of multi-detector row CT imaging reviewed

Thrush - Candida may mate when the going gets tough

Thrush - Research demonstrates potential of Miconazole as bioadhesive

Tissue Regeneration - Web site provides training on Integra tissue regenerative products

Tobacco Use - Cigarette smoke exposure may result in endothelial dysfunction

Tobacco Use - Colorado residents approve quadrupling tobacco tax for healthcare

Tobacco Use - Research points to molecule that's key to nicotine addiction

Tobacco Use - Smoking among University of Minnesota students declines

Tobacco Use - Smoking by pregnant Missouri women costing state millions

Toxicology - Endocrine disruptors in water adversely affect male fish

Toxicology - New model outlined for calculating safe levels of mercury consumption

Trachoma - Antibiotic dose may stop leading cause of blindness

Transplant Medicine - Artificial heart recipient dies

Transplant Medicine - Churches issue plea for increased rates of African American organ donation

Transplant Medicine - Hospital announces reopening of heart transplant program

Transplant Medicine - Immunosuppressive protects against coronary artery disease following transplant

Transplant Medicine - Internet organ donor freed from jail

Transplant Medicine - Matching kidney donors and recipients: age really does matter

Trauma - Study begins on blood substitute in trauma patients at the scene of injury

Tuberculosis - Mycobacterium avium strains exhibit differential virulence

Tuberculosis - Effective TB control requires treatment to include nonactive disease

Tuberculosis - Oregon Health & Science University gets grant for TB research

Tuberculosis - Partnership announced to develop novel tuberculosis drugs

Tuberculosis Genomics and Genetics - Investigation of clustered tuberculosis genotypes improves TB control

Tuberculosis Vaccine - CD27-negative CD4 T cells produce IFN-gamma upon mycobacteria challenge

Tuberculosis Vaccine - Chronic pneumonia occurs despite immune response to BCG

Tuberculosis Vaccine - Complex formation between M. tuberculosis proteins characterized

Tuberculosis Vaccine - New M. tuberculosis antigens are promising vaccine candidates

Tuberculosis Vaccine - Successful TB vaccine may need to suppress interleukin-4 activity

Tumor Suppression - Mutant p53 influences hypoxia-induced gene expression in tumor cells

Type 1 Diabetes - Hyperinsulinemia and hyperglycemia suppress muscle lipolytic activity

Type 2 Diabetes - Adjustment to type 2 diabetes in a Mexican community investigated

Type 2 Diabetes - CuraGen, partner advance investigational compound for diabetes

Type 2 Diabetes - Data demonstrate the potential of arimoclomol for the treatment of diabetes

Type 2 Diabetes - HT impairs endothelial function in postmenopausal women receiving rosiglitazone

Ulcerative Colitis - Pathway independent of p53 appears to exist related to ulcerative colitis

Ultrasound Devices - Statistical model reconciles ultrasonic scatterer size estimates

Ultrasound Imaging - Effect of viscosity on the resonance frequency of microbubbles determined

Upper Respiratory Infection - Over-the-counter drugs for upper respiratory infections may save $4.75 billion

Urinary Incontinence - Burch colposuspension outcome compared with and without abdominal hysterectomy

Urinary Incontinence - Genetics plays a role in UI, study finds

Urinary Incontinence - Study highlights therapeutic potential of duloxetine

Urinary Schistosomiasis - Monoclonal antibody-based dipstick useful for field diagnosis

Urinary Tract Infection - Study: Recurrent UTI caused by E. coli strain causing preceding UTI

Urinary Tract Infections - Cipro XR provides rapid symptom improvement in uncomplicated UTIs

Urological Oncology - Downregulated Ets2 transcription factor halts prostate cancer cell growth

Urology - Vascular endothelial growth factor shares in prostate blood flow regulation

Uterine Fibroids - FDA approves ExAblate 2000 system as noninvasive surgery for uterine fibroids

Uterine Fibroids - FDA approves ExAblate 2000 system for symptomatic uterine fibroids

Uterine Leiomyomas - 2-[F-18]fluoro-2-deoxy-D-glucose used in PET accumulates in uterine fibroids

Uterine Leiomyomas - Premyomectomy uterine artery embolization minimizes operative blood loss

Uterine Leiomyomas - Protein's potential anti-apoptotic function may play role in fibroid growth

Utilization - Study reveals critical care use in serious illness

Vaccine Adjuvant - Aluminum adjuvants reviewed

Vaccine Adjuvant - Artificial peptide induces Th2 immune response to antigens

Vaccine Adjuvant - CD40 antibody as adjuvant induces enhanced T cell responses

Vaccine Adjuvant - Non-toxic Stx derivatives from E. coli possess adjuvant activity

Vaccine Adjuvant - Protollin is novel adjuvant for intranasal vaccines

Vaccine Adjuvant - Squalene adjuvant better than aluminum hydroxide in rabies vaccine

Vaccine Adjuvant - Squalene vaccine adjuvant is safe

Vaccine Delivery - Alginate hydrogels act as controlled release protein carriers

Vaccine Development - Antigens expressed in Salmonella vectors using SPI-2 promoter

Vaccine Development - Combined phase I/II clinical trial with immunodrug candidate CYT007-TNFQb begins

Vaccine Development - License agreement reached for MedPulser DNA Delivery System in two applications

Vaccine Development - Neutralizing antibodies prevent use of human GM-CSF in macaques

Vaccine Economics - Potential conflicts of interest in vaccine economics research reviewed

Vaccine Efficacy - Data sources compared to identify veteran vaccinations

Vaccine Efficacy - IL-15 is superior to IL-2 in generating of long-lived memory T cells

Vaccine Efficacy - Vaccine efficacy estimated from household data observed over time

Vaccinia Virus - Src switches from microtubule- to actin-based vaccinia virus motility

Vascular Gene Therapy - PMM2.1.2 nanoparticles augment peri-adventitial adenoviral gene delivery

Vasopressors - Low doses of vasopressin and terlipressin can restore vasomotor tone

Vector Development - Fiber-mosaic adenovirus lends a new approach to adenoviral targeting

Vector Development - Preexisting diseases influence cytotoxic T-cell response to adenoviral vectors

Vector Development - The polymeric gene vector PLHP grants long-term gene delivery

Venous Leg Ulcers - Partnership to market wound care product Orcel in the U.S.

Ventricular Arrhythmias - Study examines molecular mechanisms that predispose hearts to arrhythmias

Ventricular Fibrillation - Approval granted for amiodarone hydrochloride

Ventricular Morphology - Na⁺/K⁺-ATPase alpha1B1 is required for cardiomyocyte morphology

Veterinary Medicine - Team combines veterinary, human medical technology to save dolphin's dorsal fin

Violence - Elder mistreatment in women needs clearer definition, more study

Viral Hepatitis - Duck hepatitis B studies explain initiation failure in human hepatitis B

Viral Meningitis - Six students treated for viral meningitis

Viral Proliferation - NS1-associated protein 1 enhances hepatitis C virus translation

Virology - CMV UL76 encodes novel virion-associated protein that inhibits viral replication

Virology - Hepatitis C virus variants are adequately represented in amplicons

Virology - Host gene expression ebbs and flows in response to enterovirus 71 infection

Virology - Polyplexes containing chitosan oligomers improve non-viral gene delivery

Vocal Fold Paralysis - Injectable calcium hydroxylapatite improves voice quality

Weight Gain - Receptor polymorphisms associated with midlife weight gain

Weight Loss - Weight loss program introduced by Michigan provider

West Nile Virus - Diagnostics company announces clearance of diagnostic assay for West Nile Virus

West Nile Virus - Human West Nile cases now total 101

West Nile Virus - U.S. FDA-approved antiviral drug in clinical trial for West Nile

Women's Health - FDA approves noninvasive procedure to treat uterine fibroids

Wound Care - Electroporation augments TGF-mediated healing in the wounds of diabetic mice

Wound Healing - Novel AP-1 target genes identified in cutaneous-repair fibroblasts

Wound Healing - Oxygenating drug infused at surgery incision site enhances healing, study shows

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