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World Disease Weekly

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Transfusion Medicine



Prestorage leucodepletion reduces transfusion reactions events



May 10th, 2005

Prestorage leucodepletion reduces transfusion reactions when compared to bedside filtration.

According to a study from Italy, "Passenger leucocytes transfused with allogenic blood are responsible for potential adverse effects.

"The impact of prestorage leucodepletion (in-line filtration) of all whole blood units on transfusion reaction rate among patients suffering from cancer was retrospectively studied, comparing all reactions following red blood cell (RBC) transfusions during 2 years of prestorage vs. 2 years of selective (bedside) leucodepletion."

"During selective leucodepletion, 5165 RBC units - of which 2745 were bedside...


Source: World Disease Weekly (2005-05-10)

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