World Disease Weekly
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Legionnaire Disease
Research from Northwestern University in the area of legionnaire disease published
July 7th, 2009
Research findings, 'Purification of Legiobactin and importance of this siderophore in lung infection by Legionella pneumophila,' are discussed in a new report. According to a study from the United States, "When cultured in a low-iron medium, Legionella pneumophila secretes a siderophore (legiobactin) that is both reactive in the chrome azurol S (CAS) assay and capable of stimulating the growth of iron-starved legionellae. Using anion-exchange high-pressure liquid chromatography (HPLC), we purified legiobactin from culture supernatants of a virulent strain of L. pneumophila." "In the process, we detected the ferrated form of legiobactin as well as other...
Source: World Disease Weekly (2009-07-07)
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