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Alcohol Use
Simple tests will help identify inactive aldehyde dehydrogenase and cancer risks
October 25th, 2005
Simple tests will help identify inactive aldehyde dehydrogenase (ALDH) and relay to subjects their own cancer risks. According to recent research published in the journal Alcohol, "Alcoholic beverages are causally related to cancer of the oral cavity, pharynx, larynx and esophagus. Ethanol is oxidized to acetaldehyde and then to acetate by alcohol dehydrogenase (ADH) and ALDH, both of which have genetic polymorphisms." "A review of case-control studies of the effects of ALDH2, ADH2 and ADH3 genotypes shows consistently positive associations between inactive heterozygous ALDH2 and the less-active ADH2 genotypes and the risk for esophageal...
Source: cancer weekly (2005-10-25)
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